Bone and Spine News
August 23, 2016

Latest Headlines
updated 5:33pm EDT

More Bone and Spine News
August 23, 2016

Osteoporosis Treatment: Systematic Global Review of Intervention Thresholds Based on FRAX

Aug. 23, 2016 — According to most current guidelines, treatment for osteoporosis is recommended in individuals with prior fragility fractures -- however for those without prior fractures, intervention thresholds ... read more

Rx Associated With Fracture Risk Infrequently Reduced After Fracture Occurrence

Aug. 22, 2016 — Is the occurrence of a fragility fracture -- where Medicare beneficiaries broke a hip, wrist or shoulder -- a missed opportunity to reduce exposure to prescription drugs associated with fracture ... read more

Osteoblastic Metastases Distinguished from Enostoses Using CT Attenuation Measurements

Aug. 18, 2016 — CT attenuation measurements can be used to distinguish untreated osteoblastic (bone-related) metastases from enostoses (benign bone lesions), a team of researchers has ... read more

Real-Time Visualization of the Function of Bone-Resorbing Cells Within Animals

Aug. 17, 2016 — Researchers have discovered a way to visualize sites where bone-resorbing cells (osteoclasts) were in the process of resorbing bone in living mice. This real-time visualization of changes in ... read more

The Fourth State of Matter, Plasma: A Technology to Improve Bone Healing?

Aug. 11, 2016 — Cold plasma looks like the glow from the "Star Wars" blue light saber but this beam of energy, made of electrons that change polarity at micro-second or nanosecond speeds, could help bones ... read more

Aug. 4, 2016 — Researchers have engineered living bone tissue to repair bone loss in the jaw, a structure that is typically difficult to restore. They grafted customized implants into pig jaws that resulted in ... read more

Forensic Research Finds Bone Density Affects Size of Bullet Holes

Aug. 3, 2016 — A proof-of-concept study finds that the density of bones in the skull affects the size of bullet holes in the skull. The finding is useful for law enforcement officials and medical examiners seeking ... read more

Clinical Usefulness of Bone Turnover Marker Concentrations in Osteoporosis

Aug. 2, 2016 — A new review finds lack of comparability between current clinical assays for CTX is evident, indicating possible limitations of combining such data for meta-analyses; to improve interpretation of ... read more

July 29, 2016 — Researchers have identified how inflammation, when precisely controlled, is crucial to bone ... read more

Study Verifies Human Gene Therapy in Model of Rare Metabolic Disorder

July 28, 2016 — Researchers are closer to finding a better way to treat children with a rare metabolic disorder called MPS ... read more

Confronted With Sepsis, Key Immune Mechanism Breaks, Scientists Find

July 28, 2016 — When the body encounters an infection, a molecular signaling system ramps up the body's infection-fighting system to produce more white blood cells to attack invading bacteria. Now researchers ... read more

Weight Loss Surgery Associated With Increased Fracture Risk

July 27, 2016 — Severely obese patients undergoing weight loss surgery are more likely to have increased fracture risks both before and after the surgical procedure compared to obese and non-obese people who ... read more

July 27, 2016 — A new study has shown that a new class of drug candidates increases bone mass by expanding bone formation (deposition of new bone) and bone turnover (a normal process of replacement of old ... read more

July 27, 2016 — By monitoring stem cell differentiation on gels that mimic the stiffness of biological tissue, researchers have identified the metabolites that stem cells use when selecting bone and cartilage fates. ... read more

Cord Blood Outperforms Matched, Unrelated Donor in Bone Marrow Transplant

July 26, 2016 — A new study finds that three years post-bone marrow transplant, the incidence of severe chronic graft-versus-host disease was 44 percent in patients who had received transplants from matched, ... read more

Scientists Test Nanoparticle Drug Delivery in Dogs With Osteosarcoma

July 25, 2016 — An engineer teamed up with a veterinarian to test a bone cancer drug delivery system in animals bigger than the standard animal model, the mouse. They chose dogs -- mammals closer in size and biology ... read more

Wrist Fractures Linked to Poor Balance in Elderly Patients

July 21, 2016 — Elderly patients suffering a low energy wrist (distal radius) fracture are more likely to have difficulties with balance, placing them at risk for future injuries, according to a new ... read more

Antibody-Based Drug for Multiple Sclerosis

July 19, 2016 — A research team has developed an antibody with potential therapeutic effects against multiple sclerosis. The study paves the way for a new strategy to control the disease, say the ... read more

July 19, 2016 — Researchers have found how sensory nerve cells work together to transmit itch signals from the skin to the spinal cord, where neurons then carry those signals to the brain. Their discovery may ... read more

ALS Research Suggests Stem Cells Be 'Aged' to Speed Progress Toward Finding Treatments

July 19, 2016 — Scientists are seeking to build an improved stem-cell model of amyotrophic lateral sclerosis (ALS) to accelerate progress toward a cure for the devastating neurological disorder. Their findings ... read more

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