Genes News
August 29, 2016

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August 29, 2016

Blinding Disease in Canines and Humans Shares Causative Gene, Pathology

Aug. 29, 2016 — Scientists report that they've directly compared the disease course of a blinding ciliopathy between humans and dogs and found remarkable ... read more

Peptide Mutants May Help to Identify Vulnerability in Tumor Cells

Aug. 29, 2016 — Researchers have presented an algorithm to detect mutant proteins based on mass spectrometry data and the results of exome sequencing. Using this new approach, the scientists have discovered unique ... read more

Probing How CRISPR-Cas9 Works

Aug. 26, 2016 — A new study reveals important new details about the inner workings of the CRISPR-Cas9 machinery in live cells that may have implications for the development of therapeutics that use the powerful gene ... read more

Aug. 26, 2016 — Researchers have identified RNA-based biomarkers that distinguish between normal, aging hematopoietic stem cells and leukemia stem cells associated with secondary acute myeloid leukemia (sAML), a ... read more

Aug. 26, 2016 — A research team has succeeded in developing 'Target-AID', a genome editing technique that does not cleave the DNA. The technique offers, through high-level editing operation, a method to ... read more

Discovery of a Novel Wnt Inhibitor With Potential to Eradicate Colorectal Cancer Stem Cells, Report Researchers

Aug. 26, 2016 — A team of researchers has announced the development of a novel small-molecule Wnt inhibitor named NCB-0846. Wnt signaling is a key pathway of cancer stem cell development. The inhibitor may provide a ... read more

Neuroscientists Stand Up for Basic Cell Biology Research

Aug. 25, 2016 — Clinical trials and translational medicine have certainly given people hope and rapid pathways to cures for some of humankind's most troublesome diseases, but now is not the time to overlook the ... read more

Aug. 25, 2016 — Functional human collagen has been impossible to create in the lab. Now, a team of researchers describes what may be the key to growing functional, natural collagen fibers outside of the body: ... read more

Aug. 25, 2016 — There are no established drugs to improve angiogenesis in diabetes. However, researchers now have identified a gene called CITED2 in a molecular pathway that may offer targets for drugs that treat ... read more

Aug. 25, 2016 — Many of the characteristics that make up a person's face, such as nose size and face width, stem from specific genetic variations, reports a team of ... read more

Altering Stem Cell Perception of Tissue Stiffness May Help Treat Musculoskeletal Disorders

Aug. 25, 2016 — A new biomaterial can be used to study how and when stem cells sense the mechanics of their surrounding environment. With further development, this biomaterial could be used to control when immature ... read more

Aug. 25, 2016 — The process of energy generation by mitochondria is closely tied to intracellular calcium regulation by a membrane gateway inside mitochondria known as the mitochondrial Ca2+ uniporter (MCU). How MCU ... read more

New Technique Takes Guesswork out of IVF Embryo Selection

Aug. 25, 2016 — Researchers have successfully trialed a new technique that could aid the process of choosing the "best" embryo for implantation, helping to boost the chances of pregnancy success from the ... read more

Coffee Drinking Habits Can Be Written in Our DNA, Study Finds

Aug. 25, 2016 — Researchers have identified a gene that appears to curb coffee consumption. People with a DNA variation in a gene called PDSS2 tend to drink fewer cups of coffee, the study ... read more

Aug. 25, 2016 — Scientists are testing a drug that could boost levels of critical protective protein in brain. In the study, the team conducted tests in a mouse model of Alzheimer's disease by raising the ... read more

Aug. 25, 2016 — New research shows that certain primate stem cells have pluripotency superior to some types derived from mice. The study maps how pluripotency differs among mice, monkeys, and humans, and illustrates ... read more

Enigmatic Molecules Maintain Equilibrium Between Fighting Infection, Inflammatory Havoc

Aug. 24, 2016 — Special RNA molecules called long non-coding RNAs are key controllers for maintaining immune health when fighting infection or preventing inflammatory disorders. The discovery offers a potential drug ... read more

Asthma Risk Increases When Child Had Bronchiolitis

Aug. 24, 2016 — Asthma risk increased 17 times when children who had bronchiolitis in the first two years of life also had a common variation of the Plasminogen activator inhibitor-1 gene, new research ... read more

Scientists Identify Spark Plug That Ignites Nerve Cell Demise in ALS

Aug. 24, 2016 — Scientists have pinpointed an enzyme that triggers rapid demise of nerve cells in people with ALS. The research team describes a molecular chain of events that culminates in the stripping of the ... read more

Barcodes Show the Blood Family Tree

Aug. 24, 2016 — By assigning a barcode to stem cells, researchers have made it possible to monitor large blood cell populations as well as individual blood cells, and study the changes over time. Among other things, ... read more

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