Resistance training prevents age-related tendon damage

"The relationship between aging and tendon disorders is not well documented," said Rita de Cassia Marqueti Durigan, Ph.D., a researcher involved in the work from the Rehabilitation Science Program, University of Brasilia, in Brasilia, Brazil. "To restrain and revert the deleterious aging process, resistance training can be used as an important tool to prevent degeneration and even restore tendon functions."

Durigan and colleagues used four groups of rats: 1) young sedentary, three months old; 2) young trained, three months old; 3) old sedentary, 21 months old; and 4) old trained, 21 months old. The sedentary rats did not perform the resistance training. The trained rats climbed a vertical ladder three times for 12 weeks, bearing progressive loads comprising 65, 85, 95, and 100 percent of their maximum carrying capacity. After the 12-week training period, the animals were euthanized for removal of the calcaneal tendon tissue. The researchers performed several assays (biochemical, histological, immunohistochemical, and molecular) to evaluate the effects of resistance training on the molecular and cellular aspects of the calcaneal tendon in young and old rats and their implications for tendon remodeling.

"It seems very plausible that the findings from this well-designed study are applicable to the comparable human situation, so the clinical potential is very signficiant," said Thoru Pederson, Ph.D., Editor-in-Chief of The FASEB Journal.