New! Sign up for our free email newsletter.
Science News
from research organizations

Perinatal BPA exposure induces chronic inflammation by modulating gut bacteria

Date:
October 10, 2017
Source:
American Society for Microbiology
Summary:
Environmental toxicants may influence inflammation-promoted chronic disease susceptibility during early life, emerging evidence from a research study in rabbits suggests. BPA exposure just before or after birth leads to reduced gut bacterial diversity, bacterial metabolites such as short-chain fatty acids (SCFA) and elevated gut permeability -- three common early markers of inflammation-promoted chronic diseases.
Share:
FULL STORY

Emerging evidence from a research study in rabbits suggests that environmental toxicants may influence inflammation-promoted chronic disease susceptibility during early life. BPA exposure just before or after birth leads to reduced gut bacterial diversity, bacterial metabolites such as short-chain fatty acids (SCFA) and elevated gut permeability -- three common early markers of inflammation-promoted chronic diseases.

The results, published this week in mSystems, a journal of the American Society for Microbiology, show that perinatal BPA exposure may cause gut bacterial dysbiosis and altered metabolite profiles that lead to chronic colon and liver inflammation. The study suggests that correcting bacterial dysbiosis induced by environmental toxins early in life may reduce the risk for chronic diseases later in life.


Story Source:

Materials provided by American Society for Microbiology. Note: Content may be edited for style and length.


Journal Reference:

  1. Lavanya Reddivari, D. N. Rao Veeramachaneni, William A. Walters, Catherine Lozupone, Jennifer Palmer, M. K. Kurundu Hewage, Rohil Bhatnagar, Amnon Amir, Mary J. Kennett, Rob Knight, Jairam K. P. Vanamala. Perinatal Bisphenol A Exposure Induces Chronic Inflammation in Rabbit Offspring via Modulation of Gut Bacteria and Their Metabolites. mSystems, 2017; 2 (5): e00093-17 DOI: 10.1128/mSystems.00093-17

Cite This Page:

American Society for Microbiology. "Perinatal BPA exposure induces chronic inflammation by modulating gut bacteria." ScienceDaily. ScienceDaily, 10 October 2017. <www.sciencedaily.com/releases/2017/10/171010133907.htm>.
American Society for Microbiology. (2017, October 10). Perinatal BPA exposure induces chronic inflammation by modulating gut bacteria. ScienceDaily. Retrieved April 23, 2024 from www.sciencedaily.com/releases/2017/10/171010133907.htm
American Society for Microbiology. "Perinatal BPA exposure induces chronic inflammation by modulating gut bacteria." ScienceDaily. www.sciencedaily.com/releases/2017/10/171010133907.htm (accessed April 23, 2024).

Explore More

from ScienceDaily

RELATED STORIES