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Newly improved glass slide turns microscopes into thermometers

Advancement could streamline and boost scientific research all over the world, help computing industry

Date:
May 2, 2018
Source:
University at Buffalo
Summary:
A new study describes how an updated version of the microscope slide can enable scientists to see tiny objects while also measuring their temperature. The advancement, made possible by a new transparent, has the potential to streamline and enhance scientific research worldwide, from clandestine government biology labs to high school chemistry classes. It may also have implications in computers, electronics and other industries.
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The humble glass microscope slide may be primed for a makeover.

A study published online today (May 2, 2018) in the journal Nature Communications describes how an updated version of this centuries-old tool can now enable scientists to see tiny objects while also measuring their temperature.

The advancement, made possible by a new transparent coating at the forefront of optics theory, has the potential to streamline and enhance scientific research worldwide, from clandestine government biology labs to high school chemistry classes.

It may also have implications in other industries, such as computers and electronics, whose products require measurement and control of heat in highly confined spaces.

"We have instruments that magnify incredibly small objects. And we have tools that measure heat, like infrared thermometers. But we haven't been able to combine them in a low-cost and reliable manner. This new coating takes a big step in that direction," says the study's co-lead author Ruogang Zhao, PhD, assistant professor in the University at Buffalo Department of Biomedical Engineering.

The department is a multidisciplinary unit formed by UB's School of Engineering and Applied Sciences and the Jacobs School of Medicine and Biomedical Sciences at UB.

Zhao collaborated with researchers at the University of Pennsylvania, including co-lead author Liang Feng, PhD, assistant professor of materials science and engineering, and electrical and systems engineering.

For decades, researchers have tried to combine thermal imaging and microscopy. Images produced from systems that use thermocouples lack resolution and are often too coarse for modern science. Terahertz and infrared thermal mapping techniques interfere with the microscope's lenses. Other techniques are expensive and time-consuming.

The new coating is made of a layer of acrylic glass (the same material used in most eyeglasses) that's sandwiched between two layers of transparent gold. The gold is transparent because it's only 20 nanometers thick; a typical sheet of paper is 100,000 nanometers thick.

Engineers fabricated the coating so that "exceptional points" -- the sweet spots where unusual light behavior happens -- can develop within the tri-layered structure. The coating, which significantly enhances the slide's sensitivity to light detection, would be added to slides during the manufacturing process. Either the slide or cover slip could receive the coating.

To make use of the new coating, a laser is needed. Zhao says a common helium-neon laser, which can be seamlessly integrated with most microscopes, will do the job.

Common slides, which are often bought in bulk, typically cost around 5 cents. The new coating would likely add a few pennies to the cost, Zhao says.

The research is supported by funding from the National Science Foundation and the National Institutes of Health.


Story Source:

Materials provided by University at Buffalo. Note: Content may be edited for style and length.


Journal Reference:

  1. Han Zhao, Zhaowei Chen, Ruogang Zhao, Liang Feng. Exceptional point engineered glass slide for microscopic thermal mapping. Nature Communications, 2018; 9 (1) DOI: 10.1038/s41467-018-04251-3

Cite This Page:

University at Buffalo. "Newly improved glass slide turns microscopes into thermometers." ScienceDaily. ScienceDaily, 2 May 2018. <www.sciencedaily.com/releases/2018/05/180502174914.htm>.
University at Buffalo. (2018, May 2). Newly improved glass slide turns microscopes into thermometers. ScienceDaily. Retrieved March 28, 2024 from www.sciencedaily.com/releases/2018/05/180502174914.htm
University at Buffalo. "Newly improved glass slide turns microscopes into thermometers." ScienceDaily. www.sciencedaily.com/releases/2018/05/180502174914.htm (accessed March 28, 2024).

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