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Scientists test an anti-aging cream that actually works

Date:
September 15, 2025
Source:
KeAi Communications Co., Ltd.
Summary:
A 28-day trial showed that pterostilbene cream improved wrinkles, skin firmness, collagen, and pore size far better than a control emulsion. The results highlight pterostilbene as a promising natural ingredient for next-generation anti-aging skincare.
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Against the backdrop of high market demand for effective anti-ageing cosmetics, a team of Chinese researchers assessed the clinical effectiveness of a 0.1 % pterostilbene-containing skincare emulsion against a control emulsion over 28 days with 31 participants.

The study employed a double-blind, split-face design, comparing the left and right sides of the face and using advanced instruments along with subject self-assessments. The set of instruments used, together with the findings, is reported in the team's published article in the Journal of Dermatologic Science and Cosmetic Technology.

"Our results indicated that the pterostilbene emulsion remarkably improved skin elasticity, firmness, and reduced wrinkles, such as forehead, undereye, and Crow's feet wrinkles, shares co-author Zhiyuan Chen, Founder of Guangzhou Luanying Cosmetics Co., Ltd. "It also increased the thickness of the epidermis layer, enhanced collagen and elastic fibers, and minimized skin pores."

Compared to the control emulsion, the pterostilbene emulsion brought about statistically significant improvements, and all subjects expressed higher satisfaction with the pterostilbene emulsion. These results collectively demonstrated the superior anti-aging efficacy of the pterostilbene emulsion through multiple mechanisms.

According to corresponding author Xueping Chen, the findings advance our understanding of pterostilbene's role in skincare by providing evidence of its potent anti-ageing effects and supporting its use as an active ingredient in cosmetics. "It also offers a new perspective on natural compounds' applications in the skincare industry," says Chen. "The significant improvements in various skin parameters and the subjects' positive feedback highlight the effectiveness of pterostilbene, which may change the way we approach anti-ageing skincare formulations."

The authors propose a longer study period to fully understand the impact of pterostilbene.


Story Source:

Materials provided by KeAi Communications Co., Ltd.. Note: Content may be edited for style and length.


Journal Reference:

  1. Zongxiao Cen, Zhiyuan Chen, Ding Wang, Yuqin Zuo, Junyuan Chen, Xueping Chen. Anti-aging Efficacy of a 0.1 % Pterostilbene Skincare Emulsion: A 28-Day Clinical Trial. Journal of Dermatologic Science and Cosmetic Technology, 2025; 2 (2): 100083 DOI: 10.1016/j.jdsct.2025.100083

Cite This Page:

KeAi Communications Co., Ltd.. "Scientists test an anti-aging cream that actually works." ScienceDaily. ScienceDaily, 15 September 2025. <www.sciencedaily.com/releases/2025/09/250914205851.htm>.
KeAi Communications Co., Ltd.. (2025, September 15). Scientists test an anti-aging cream that actually works. ScienceDaily. Retrieved September 15, 2025 from www.sciencedaily.com/releases/2025/09/250914205851.htm
KeAi Communications Co., Ltd.. "Scientists test an anti-aging cream that actually works." ScienceDaily. www.sciencedaily.com/releases/2025/09/250914205851.htm (accessed September 15, 2025).

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