1
2
July 20, 2022 — Scientists have investigated a compound called BnOCPA (benzyloxy-cyclopentyladenosine), found to be a potent and selective analgesic which is non-addictive in test model systems. BnOCPA also has a ...
Sep. 20, 2023 — New research has identified an alternative signaling pathway in the brain of mice that relieves pain, even in animals that have developed tolerance to opioids. The study also showed that pain relief ...
Nov. 30, 2022 — A collaboration of scientists found a novel way to render benign the worst side effects of ...
Aug. 31, 2022 — A new study points to possible new treatments for chronic pain with a surprising link to lung cancer. Findings of the research, conducted in laboratory mouse models, open up multiple therapeutic ...
Aug. 24, 2021 — Opioids are powerful painkillers but their use is hindered because patients become tolerant to them, requiring higher and higher doses, and overdoses can cause respiratory depression and death. A ...
Sep. 9, 2021 — Researchers have made a breakthrough discovery that could pave the way for the development of novel non-opioid painkillers (analgesics) to safely and effectively treat neuropathic ...
July 6, 2022 — Opioids are the gold standard for treatment of chronic and acute pain; however, their use may result in significant gastrointestinal side effects, including nausea, vomiting, and constipation. The ...
Jan. 12, 2023 — New work provides a comprehensive structural framework that should help drug developers rationally design safer drugs to relieve severe ...
Feb. 22, 2022 — In a study of vaginal births in New York State hospitals, labor neuraxial analgesia -- having an epidural or combined spinal and epidural -- was associated with a decreased risk of severe maternal ...
Mar. 31, 2022 — Global opioid sales increased by an estimated 4% annually from 2015 to 2019, but massive disparities in access to essential pain relief medications persist between countries, a new study ...
