New! Sign up for our free email newsletter.
Reference Terms
from Wikipedia, the free encyclopedia

Chemotherapy

Chemotherapy is the use of chemical substances to treat disease. In its modern-day use, it refers primarily to cytotoxic drugs used to treat cancer. Cancer is the uncontrolled growth of cells due to damage to DNA (mutations) and, occasionally, due to an inherited propensity to develop certain tumours. Autoimmune diseases arise from an overactive immune response of the body against substances and tissues normally present in the body; in other words, the body attacks its own cells. In contrast, transplant rejection happens because a normal healthy human immune system can distinguish foreign tissues and attempts to destroy them. Also the reverse situation, called graft-versus-host disease, may take place.

Broadly, most chemotherapeutic drugs work by impairing mitosis (cell division), effectively targeting fast-dividing cells. As these drugs cause damage to cells they are termed cytotoxic. Some drugs cause cells to undergo apoptosis (so-called "cell suicide").

Related Stories
 


Health & Medicine News

November 6, 2025

Weill Cornell researchers uncovered how free radicals from astrocyte mitochondria can fuel dementia. Using new compounds that target these radicals at their source, they slowed brain inflammation and neuronal damage in mice. The findings reveal a ...
Researchers have created a bioinspired gel that can regenerate tooth enamel by mimicking natural growth processes. The fluoride-free material forms a mineral-rich layer that restores enamel’s strength and structure while preventing decay. It can ...
A Northwestern team transformed a common chemotherapy drug into a powerful, targeted cancer therapy using spherical nucleic acids. The redesign dramatically boosted drug absorption and cancer-killing power while avoiding side effects. This ...
Virginia Tech researchers have shown that memory loss in aging may be reversible. Using CRISPR tools, they corrected molecular disruptions in the hippocampus and amygdala, restoring memory in older rats. Another experiment revived a silenced memory ...
Meditation is widely praised for its mental health benefits, but new research shows that it can also produce unexpected side effects for some people—from anxiety and dissociation to functional impairment. Psychologist Nicholas Van Dam and his team ...
Most U.S. adults don’t realize alcohol raises cancer risk, and drinkers themselves are the least aware. Scientists say targeting these misbeliefs could significantly reduce alcohol-related cancer ...
Researchers discovered how rabies virus exerts massive control over host cells with very few genes. A key viral protein changes shape and binds RNA, allowing it to infiltrate different cellular systems. This adaptability could explain the power of ...
Cockroach infestations don’t just bring creepy crawlers, they fill homes with allergens and bacterial toxins that can trigger asthma and allergies. NC State researchers found that larger infestations meant higher toxin levels, especially from ...
Researchers have, for the first time, estimated how quickly E. coli bacteria can spread between people — and one strain moves as fast as swine flu. Using genomic data from the UK and Norway, scientists modeled bacterial transmission rates and ...
Scientists at Mizzou have identified two small molecules, agmatine and thiamine, that could both reveal and fight glaucoma. Their research shows these compounds are lower in glaucoma patients, suggesting they may serve as early warning markers. Even ...
A new compound called CMX410 may change the fight against tuberculosis. It targets a weak point in the bacteria’s defenses, even in drug-resistant forms of the disease. Created using a cutting-edge chemistry method, the drug shows promise for ...
Walking a few thousand steps daily may help hold off Alzheimer’s for years, a Mass General Brigham study found. Even moderate physical activity slowed both cognitive decline and the buildup of harmful tau proteins in the brain. The researchers say ...

Latest Headlines

updated 12:56 pm ET