Featured Research

from universities, journals, and other organizations

Chickens Succumbing To Virus Formerly Avoided By Vaccination

Date:
May 3, 2001
Source:
University Of Illinois At Urbana-Champaign
Summary:
A virus common to poultry is outfoxing a long-used vaccine, apparently through natural genetic engineering and by using strategies to survive environmental insults, says a University of Illinois researcher who has been tracking new outbreaks around the world. A new form of fowlpox, he said, now threatens poultry production and requires a new vaccine strategy.

CHAMPAIGN, Ill. — A virus common to poultry is outfoxing a long-used vaccine, apparently through natural genetic engineering and by using strategies to survive environmental insults, says a University of Illinois researcher who has been tracking new outbreaks around the world. A new form of fowlpox, he said, now threatens poultry production and requires a new vaccine strategy.

Related Articles


Live vaccines have been used for more than 50 years to protect commercial poultry against fowlpox – a slow-spreading infection in birds for which there is no treatment. A new viral strain, carrying genes from an unrelated avian virus, has arisen to cause disease in previously vaccinated chickens in Arkansas, California, Indiana, Minnesota, Nebraska, New York and Pennsylvania.

Deoki N. Tripathy, a professor of veterinary pathobiology in the UI College of Veterinary Medicine, summarized the situation in a presentation during the 50th Western Poultry Disease Conference in March at the University of California at Davis.

“In most of these occurrences, the diphtheritic form of the disease, which attacks the eyes, throats and trachea, results in high mortality,” Tripathy said. “Reduced egg production with significant economic losses in affected layer flocks also has been observed.” A molecular analysis of the new form of the virus in the United States and in Australia shows the integration of a retrovirus, avian reticuloendotheliosis virus (REV), into its genome. While fowlpox virus vaccines carry a portion of REV, the new strains contain intact REV.

In the February issue of the Journal of Virology, Tripathy reported that the fowlpox virus also has two other genes. One encodes for an enzyme, photolyase, which allows for the repair of DNA damaged by sunlight, and the other for a protein that shields the virus from environmental damage.

“The virus has acquired several genes that are not vital for its multiplication but provide a good strategy for prolonged survival,” he said. Since fowlpox is among the largest of viruses – more than 200 genes encoding for essential and non-essential proteins – it is not surprising to find “spontaneous, natural genetic engineering” occurring between distinct viruses attacking the same birds, he said. In large poultry operations, birds face multiple pathogens.

Fowlpox occurs as a dry pox, which results in wart-like nodules on the skin that turn to scabs, and/or a usually fatal wet pox that affects the oral cavity and upper respiratory system. Most birds recover from dry pox within three to five weeks but not without losses in egg production or growth.

The scabs from dry pox that fall from infected birds can contain millions of virus particles and survive for months in the poultry environment. Infection can spread into injured or lacerated skin, and by birds inhaling dust containing the particles. Mosquitoes also can transmit the disease.

Tripathy and his colleagues are researching a new generation of poultry vaccines.


Story Source:

The above story is based on materials provided by University Of Illinois At Urbana-Champaign. Note: Materials may be edited for content and length.


Cite This Page:

University Of Illinois At Urbana-Champaign. "Chickens Succumbing To Virus Formerly Avoided By Vaccination." ScienceDaily. ScienceDaily, 3 May 2001. <www.sciencedaily.com/releases/2001/05/010503092806.htm>.
University Of Illinois At Urbana-Champaign. (2001, May 3). Chickens Succumbing To Virus Formerly Avoided By Vaccination. ScienceDaily. Retrieved December 22, 2014 from www.sciencedaily.com/releases/2001/05/010503092806.htm
University Of Illinois At Urbana-Champaign. "Chickens Succumbing To Virus Formerly Avoided By Vaccination." ScienceDaily. www.sciencedaily.com/releases/2001/05/010503092806.htm (accessed December 22, 2014).

Share This


More From ScienceDaily



More Plants & Animals News

Monday, December 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Christmas Kissing Good for Health

Christmas Kissing Good for Health

Reuters - Innovations Video Online (Dec. 22, 2014) Scientists in Amsterdam say couples transfer tens of millions of microbes when they kiss, encouraging healthy exposure to bacteria. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Brain-Dwelling Tapeworm Reveals Genetic Secrets

Brain-Dwelling Tapeworm Reveals Genetic Secrets

Reuters - Innovations Video Online (Dec. 22, 2014) Cambridge scientists have unravelled the genetic code of a rare tapeworm that lived inside a patient's brain for at least four year. Researchers hope it will present new opportunities to diagnose and treat this invasive parasite. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
New Fish Species Discovered, Setting Record for World's Deepest

New Fish Species Discovered, Setting Record for World's Deepest

Buzz60 (Dec. 22, 2014) A new species of fish is discovered living five miles beneath the ocean surface, making it the deepest living fish on earth. Jen Markham has the story. Video provided by Buzz60
Powered by NewsLook.com
Earthworms Provide Cancer-Fighting Bacteria

Earthworms Provide Cancer-Fighting Bacteria

Reuters - Innovations Video Online (Dec. 21, 2014) Polish scientists isolate bacteria from earthworm intestines which they say may be used in antibiotics and cancer treatments. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins