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Mice Point To Genetic Basis For Obsessive Grooming

Date:
January 8, 2002
Source:
Howard Hughes Medical Institute
Summary:
A gene involved in setting up the mammalian body plan also appears to control grooming behavior in mice. Researchers who knocked out a specific homeobox, or Hox, gene in mice also noted that the mice groomed themselves excessively -- creating bald spots and skin wounds. The discovery suggests that the Hox genes, a large family of development-controlling genes, might also serve as behavioral regulators in the adult brain.

January 4, 2002 -- A gene involved in setting up the mammalian body plan also appears to control grooming behavior in mice. Researchers who knocked out a specific homeobox, or Hox, gene in mice also noted that the mice groomed themselves excessively -- creating bald spots and skin wounds. The discovery suggests that the Hox genes, a large family of development-controlling genes, might also serve as behavioral regulators in the adult brain. Studies of the gene family could yield important insights into the genetic basis of compulsive behavior in humans.


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The above story is based on materials provided by Howard Hughes Medical Institute. Note: Materials may be edited for content and length.


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Howard Hughes Medical Institute. "Mice Point To Genetic Basis For Obsessive Grooming." ScienceDaily. ScienceDaily, 8 January 2002. <www.sciencedaily.com/releases/2002/01/020104074606.htm>.
Howard Hughes Medical Institute. (2002, January 8). Mice Point To Genetic Basis For Obsessive Grooming. ScienceDaily. Retrieved April 24, 2014 from www.sciencedaily.com/releases/2002/01/020104074606.htm
Howard Hughes Medical Institute. "Mice Point To Genetic Basis For Obsessive Grooming." ScienceDaily. www.sciencedaily.com/releases/2002/01/020104074606.htm (accessed April 24, 2014).

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