Featured Research

from universities, journals, and other organizations

Genes Involved In Cell Growth And Cell Division Identified

Date:
February 23, 2006
Source:
University of Helsinki
Summary:
A recent study shows that hundreds of genes contribute to cell growth and cell division. For the first time these genes, many of which are potential contributors to cancer, have been mapped in a single systematic study. Finnish researchers have identified genes contributing to cell growth and cell division by systematic silencing of most of the genes in the fruit fly, Drosophila melanogaster. The results are published in the February 23 issue of the journal Nature.

A recent study shows that hundreds of genes contribute to cell growth and cell division. For the first time these genes, many of which are potential contributors to cancer, have been mapped in a single systematic study.

The group led by Professor Jussi Taipale (University of Helsinki and National Public Health Institute of Finland) has identified genes contributing to cell growth and cell division by systematic silencing of most of the genes in the fruit fly, Drosophila melanogaster. The results are published in the February 23. issue of the journal Nature.

The group of Jussi Taipale belongs to the Molecular and Cancer Biology Research Program of the Faculty of Medicine of the University of Helsinki, and the Department of Molecular Medicine of the National Public Health Institute, Finland. The group is part of the Finnish Academy Centre of Excellence for the Translational Genome-Scale Biology.

Drosophila cells are an excellent model system to also understand the regulation of growth in human cells as the core machinery involved in this process is very similar in all multicellular organisms from insects to humans. Because the regulation of cell growth is central for embryonic development as well as cancer, it is highly important to have a holistic view on these processes.

This study belongs to the emerging field of systems biology, which aims to a comprehensive understanding of cellular mechanisms by carrying out large-scale experiments and combining the data using bioinformatics. The screening of the genes was performed in High Throughput Center of the University of Helsinki.

The genome sequencing projects have revealed a large number of genes with unknown functions. The current study lead by professor Taipale identified a number of such functionally unannotated genes in addition to the identification of the majority of known growth regulators. This set of genes provides an excellent starting point for future studies concentrating on the interactions between genes involved in cell growth.

###

The research was performed by Mikael Bj๖rklund, Minna Taipale, Markku Varjosalo, Juha Saharinen, Juhani Lahdenperไ, and Jussi Taipale. This study was financed by the Finnish Academy, Biocentrum Helsinki, University of Helsinki, The Sigrid Juselius Foundation, The Finnish Cultural Foundation, The Maud Kuistila Memorial Foundation and the Finnish Cancer Organisations.


Story Source:

The above story is based on materials provided by University of Helsinki. Note: Materials may be edited for content and length.


Cite This Page:

University of Helsinki. "Genes Involved In Cell Growth And Cell Division Identified." ScienceDaily. ScienceDaily, 23 February 2006. <www.sciencedaily.com/releases/2006/02/060223083212.htm>.
University of Helsinki. (2006, February 23). Genes Involved In Cell Growth And Cell Division Identified. ScienceDaily. Retrieved July 31, 2014 from www.sciencedaily.com/releases/2006/02/060223083212.htm
University of Helsinki. "Genes Involved In Cell Growth And Cell Division Identified." ScienceDaily. www.sciencedaily.com/releases/2006/02/060223083212.htm (accessed July 31, 2014).

Share This




More Plants & Animals News

Thursday, July 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Raw: Thousands Flocking to German Crop Circle

Raw: Thousands Flocking to German Crop Circle

AP (July 30, 2014) — Thousands of people are trekking to a Bavarian farmer's field to check out a mysterious set of crop circles. (July 30) Video provided by AP
Powered by NewsLook.com
Concern Grows Over Worsening Ebola Crisis

Concern Grows Over Worsening Ebola Crisis

AFP (July 30, 2014) — Pan-African airline ASKY has suspended all flights to and from the capitals of Liberia and Sierra Leone amid the worsening Ebola health crisis, which has so far caused 672 deaths in Guinea, Liberia and Sierra Leone. Duration: 00:43 Video provided by AFP
Powered by NewsLook.com
At Least 20 Chikungunya Cases in New Jersey

At Least 20 Chikungunya Cases in New Jersey

AP (July 30, 2014) — At least 20 New Jersey residents have tested positive for chikungunya, a mosquito-borne virus that has spread through the Caribbean. (July 30) Video provided by AP
Powered by NewsLook.com
Xtreme Eating: Your Daily Caloric Intake All On One Plate

Xtreme Eating: Your Daily Caloric Intake All On One Plate

Newsy (July 30, 2014) — The Center for Science in the Public Interest released its 2014 list of single meals with whopping calorie counts. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

    Technology News



      Save/Print:
      Share:  

      Free Subscriptions


      Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

      Get Social & Mobile


      Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

      Have Feedback?


      Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
      Mobile iPhone Android Web
      Follow Facebook Twitter Google+
      Subscribe RSS Feeds Email Newsletters
      Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins