Featured Research

from universities, journals, and other organizations

Evolution Of Influenza A Virus

Date:
December 1, 2006
Source:
Public Library of Science
Summary:
An understanding of the evolutionary dynamics of the influenza virus determines scientists' ability to survey and control the virus.

An understanding of the evolutionary dynamics of the influenza virus determines scientists' ability to survey and control the virus. In a new study, published online in the open-access journal PLoS Pathogens, Dr. Eddie C. Holmes of the Department of Biology at Pennsylvania State University and colleagues at the National Institutes of Health, the Wordsworth Center and the Institute for Genomic Research used genomic analysis to investigate the evolutionary properties of the H3N2 subtype of human influenza A virus.

Related Articles


The authors, in the first population-based study of its kind, collected a sample group of 413 complete influenza genomes from across New York State. Comparative analysis of the samples revealed genetically distinct viral strains circulate across the state within any one season and occasionally exchange genes through reassortment.

These results indicate that adaptive evolution occurs only sporadically in influenza virus, and that influenza virus diversity and evolution is strongly affected by chance events, such as reassortment between strains coinfecting a host or the introduction of a particular variant from elsewhere. These factors make predicting future patterns of influenza virus evolution more difficult, as vaccine strain selection then becomes dependent upon intensive surveillance, whole-genome sequencing, and phenotypic analysis.

This study supported by Cooperative Research 14 Agreement Number U50/CCU223671 from the Centers for Disease Control and Prevention. Laboratory support was provided by M. Kleabonas and R. Bennett at the Wadsworth Center.

Citation: Nelson MI, Simonsen L, Viboud C, Miller MA, Taylor J, et al. (2006) Stochastic processes are key determinants of short-term evolution in influenza A virus. PLoS Pathog 2(12): e125. doi:10.1371/journal.ppat.0020125 (http://dx.doi.org/10.1371/journal.ppat.0020125)


Story Source:

The above story is based on materials provided by Public Library of Science. Note: Materials may be edited for content and length.


Cite This Page:

Public Library of Science. "Evolution Of Influenza A Virus." ScienceDaily. ScienceDaily, 1 December 2006. <www.sciencedaily.com/releases/2006/12/061201110251.htm>.
Public Library of Science. (2006, December 1). Evolution Of Influenza A Virus. ScienceDaily. Retrieved February 1, 2015 from www.sciencedaily.com/releases/2006/12/061201110251.htm
Public Library of Science. "Evolution Of Influenza A Virus." ScienceDaily. www.sciencedaily.com/releases/2006/12/061201110251.htm (accessed February 1, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, February 1, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Hikers Rescued After Fall from Oregon Mountain

Hikers Rescued After Fall from Oregon Mountain

AP (Feb. 1, 2015) Two climbers who were hurt in a fall on Mount Hood are now being treated for their injuries. Rescue officials say they were airlifted off the mountain Saturday afternoon by an Oregon National Guard helicopter. (Feb. 2) Video provided by AP
Powered by NewsLook.com
Smart Glasses Augment Reality to Help Visually Impaired

Smart Glasses Augment Reality to Help Visually Impaired

Reuters - Innovations Video Online (Feb. 1, 2015) New augmented reality smart glasses developed by researchers at Oxford University can help people with visual impairments improve their vision by providing depth-based feedback, allowing users to "see" better. Joel Flynn reports. Video provided by Reuters
Powered by NewsLook.com
Flu Season Hitting Elderly Hard

Flu Season Hitting Elderly Hard

Reuters - US Online Video (Jan. 31, 2015) The CDC says this year&apos;s flu season is hitting people 65 years of age and older especially hard. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
CDC: Get Vaccinated for Measles

CDC: Get Vaccinated for Measles

Reuters - US Online Video (Jan. 30, 2015) The CDC is urging people to get vaccinated for measles amid an outbreak that began at Disneyland and has now infected more than 90 people. Linda So reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins