Featured Research

from universities, journals, and other organizations

Organism That Causes Buruli Ulcer Has Been Isolated And Characterized

Date:
March 26, 2008
Source:
Public Library of Science
Summary:
Scientists have for the first time isolated from the environment and fully characterized the organism that causes Buruli ulcer. The study lends support to the idea that the organism, Mycobacterium ulcerans, is transmitted to humans from environmental aquatic niches, rather than from person-to-person.

An international team of 17 researchers from four countries has for the first time isolated from the environment and fully characterized the organism that causes Buruli ulcer. The study lends support to the idea that the organism, Mycobacterium ulcerans, is transmitted to humans from environmental aquatic niches, rather than from person to person.

Buruli ulcer is a neglected, devastating, necrotizing disease, sometimes producing massive, disfiguring ulcers, with huge social impact. The disease occurs predominantly in impoverished, humid, tropical, rural areas of Africa, where the incidence has been increasing, surpassing tuberculosis and leprosy (two other diseases caused by mycobacteria) in some regions. Besides being a disease of the poor, Buruli ulcer is a poverty-promoting chronic infectious disease.

Although it has long been believed that Mycobacterium ulcerans is an environmental pathogen transmitted to humans from its aquatic niches, until now the organism has not been isolated in pure culture from environmental sources.

Franηoise Portaels (Institute of Tropical Medicine, Antwerpen, Belgium) and colleagues in Ghana, Portugal, and the US, now present details of the isolation and characterization of a Mycobacterium ulcerans strain from the environment. To the best of their knowledge, this is the first time that the organism has ever been isolated and fully characterized from the environment.

The isolated strain has microbiological features typical of African strains of Mycobacterium ulcerans and was isolated from an aquatic insect (the Water Strider) from a Buruli ulcer-endemic area in Benin, West Africa.

"Our findings support the concept that Mycobacterium ulcerans is a pathogen of humans with an aquatic environmental niche," say the authors "and will have positive consequences for the control of this neglected and socially important tropical disease."

In a related expert commentary, Tim Stinear (Monash University, Clayton, Victoria, Australia) and Paul Johnson (Austin Hospital, Heidelberg, Australia), who were not involved in the study, say that the new study is "a major achievement and will serve as the definitive reference point for scientists' intent on revealing the ecology, environmental reservoir, and precise mode of transmission of Mycobacterium ulcerans."

Journal reference: Portaels F, Meyers WM, Ablordey A, Castro AG, Chemlal K, et al. (2008) First Cultivation and Characterization of Mycobacterium ulcerans from the Environment. PLoS Negl Trop Dis 2(3): e178. doi:10.1371/journal.pntd.0000178


Story Source:

The above story is based on materials provided by Public Library of Science. Note: Materials may be edited for content and length.


Cite This Page:

Public Library of Science. "Organism That Causes Buruli Ulcer Has Been Isolated And Characterized." ScienceDaily. ScienceDaily, 26 March 2008. <www.sciencedaily.com/releases/2008/03/080325212836.htm>.
Public Library of Science. (2008, March 26). Organism That Causes Buruli Ulcer Has Been Isolated And Characterized. ScienceDaily. Retrieved August 1, 2014 from www.sciencedaily.com/releases/2008/03/080325212836.htm
Public Library of Science. "Organism That Causes Buruli Ulcer Has Been Isolated And Characterized." ScienceDaily. www.sciencedaily.com/releases/2008/03/080325212836.htm (accessed August 1, 2014).

Share This




More Health & Medicine News

Friday, August 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

House Republicans Vote to Sue Obama Over Healthcare Law

House Republicans Vote to Sue Obama Over Healthcare Law

Reuters - US Online Video (July 31, 2014) — The Republican-led House of Representatives votes to sue President Obama, accusing him of overstepping his executive authority in making changes to the Affordable Care Act. Mana Rabiee reports. Video provided by Reuters
Powered by NewsLook.com
Despite Health Questions, E-Cigs Are Beneficial: Study

Despite Health Questions, E-Cigs Are Beneficial: Study

Newsy (July 31, 2014) — Citing 81 previous studies, new research out of London suggests the benefits of smoking e-cigarettes instead of regular ones outweighs the risks. Video provided by Newsy
Powered by NewsLook.com
Dangerous Bacteria Kills One in Florida

Dangerous Bacteria Kills One in Florida

AP (July 31, 2014) — Sarasota County, Florida health officials have issued a warning against eating raw oysters and exposing open wounds to coastal and inland waters after a dangerous bacteria killed one person and made another sick. (July 31) Video provided by AP
Powered by NewsLook.com
Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) — Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins