Featured Research

from universities, journals, and other organizations

Mitosis Gets Harder Thanks To New Gene Discovery

Date:
April 6, 2008
Source:
University of Bath
Summary:
A biological process taught to every pupil studying science at high school has just become a little more complicated thanks to a new discovery. Scientists have found that a protein called RASSF7 is essential for mitosis, the process by which a cell divides in two.

A biological process taught to every student studying biology has just become a little more complicated thanks to a new discovery. Scientists from the University of Bath have found that a protein called RASSF7 is essential for mitosis, the process by which a cell divides in two.

Related Articles


In research published in the journal Molecular Biology of the Cell, the scientists have shown that the protein is essential for building the microtubules that allow the two halves of the cell to slide apart.

“What makes mitosis so interesting is that it is one of the biological processes that everyone remembers from their days at school,” said Dr Andrew Chalmers from the University’s Department of Biology & Biochemistry.

“As well as being one of Nature’s most important processes, our interest in mitosis stems from the fact that if you want to kill cancer cells, then stopping them from dividing is a useful way of doing this.

“Several cancer treatments block cell division by targeting microtubules, Taxol is a well known example. It is even possible that RASSF7 might be a future drug target”.

During the different phases of mitosis the pairs of chromosomes within the cell condense and attach to microtubule fibres that pull the sister chromatids to opposite sides of the cell.

The cell then divides in cytokinesis, to produce two identical daughter cells.

RASSF7 is the latest of a battery of proteins involved in managing the complex process of mitosis. “During mitosis, the chromosomes containing the DNA are pulled apart in two halves by an array of microtubules centred on the centrosomes,” said Dr Chalmers.

“Without the RASSF7 protein, the microtubules do not develop properly and cell division is halted. “This is the first functional study of this protein, and we hope to extend our knowledge of how it works in the future.”

The work was carried out in Dr Chalmers laboratory by Dr Victoria Sherwood and two final year undergraduate project students from the University, Ria Manbodh and Carol Sheppard.

The research was funded by the Medical Research Council.


Story Source:

The above story is based on materials provided by University of Bath. Note: Materials may be edited for content and length.


Cite This Page:

University of Bath. "Mitosis Gets Harder Thanks To New Gene Discovery." ScienceDaily. ScienceDaily, 6 April 2008. <www.sciencedaily.com/releases/2008/04/080403104400.htm>.
University of Bath. (2008, April 6). Mitosis Gets Harder Thanks To New Gene Discovery. ScienceDaily. Retrieved January 25, 2015 from www.sciencedaily.com/releases/2008/04/080403104400.htm
University of Bath. "Mitosis Gets Harder Thanks To New Gene Discovery." ScienceDaily. www.sciencedaily.com/releases/2008/04/080403104400.htm (accessed January 25, 2015).

Share This


More From ScienceDaily



More Plants & Animals News

Sunday, January 25, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Florida Might Legalize Black Bear Hunting

Florida Might Legalize Black Bear Hunting

Newsy (Jan. 24, 2015) A string of black bear attacks has Florida officials considering lifting the ban on hunting the animals to control their population. Video provided by Newsy
Powered by NewsLook.com
Ebola Killing Large Portion Of Ape Population

Ebola Killing Large Portion Of Ape Population

Newsy (Jan. 23, 2015) Experts estimate Ebola has wiped out one-third of the world&apos;s gorillas and chimpanzees. Video provided by Newsy
Powered by NewsLook.com
Controversy Shrouds Captive Killer Whale in Miami

Controversy Shrouds Captive Killer Whale in Miami

Reuters - Light News Video Online (Jan. 23, 2015) Activists hope the National Oceanic and Atmospheric Agency (NOAA) will label killer whales endangered, allowing lawyers to sue a Miami aquarium to release an orca into the wild after 44 years. Jillian Kitchener reports. Video provided by Reuters
Powered by NewsLook.com
‘Healthy’ Foods That Surprisingly Pack on Pounds

‘Healthy’ Foods That Surprisingly Pack on Pounds

Buzz60 (Jan. 23, 2015) Some &apos;healthy&apos; foods are actually fattening. Fitness and nutrition expert John Basedow (@JohnBasedow) shines a light on the sneaky foods like nuts, seeds, granola, trail mix, avocados, guacamole, olive oil, peanut butter, fruit juices and salads that are good for you...but not so much for your waistline. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins