Featured Research

from universities, journals, and other organizations

Aerosol Toxins From Red Tides May Cause Long-term Health Threat

Date:
July 9, 2008
Source:
National Oceanic And Atmospheric Administration
Summary:
An algal toxin commonly inhaled in sea spray, attacks and damages DNA in the lungs of laboratory rats. The findings document how the body's way of disposing the toxin inadvertently converts it to a molecule that damages DNA. Human inhalation of brevetoxins produced by the red tide organism, Karenia brevis, is an increasing public health concern.

Red tide.
Credit: NOAA

NOAA scientists reported in the current issue of the journal Environmental Health Perspectives that an algal toxin commonly inhaled in sea spray, attacks and damages DNA in the lungs of laboratory rats. The findings document how the body's way of disposing the toxin inadvertently converts it to a molecule that damages DNA. Human inhalation of brevetoxins produced by the red tide organism, Karenia brevis, is an increasing public health concern.

Related Articles


The scientists, led by John Ramsdell of NOAA's Center for Environmental Health and Biomolecular Research in Charleston, S.C., determined that brevetoxins react with DNA of lung tissue and attach to the DNA-bases that code genetic information. The linkage of chemicals in the environment to DNA is a first step for many cancer causing agents and can lead to mutations in genes that normally prevent the formation of cancers.

The red tide toxin, brevetoxin, has long been recognized as a cause of both neurotoxic poisoning after both consumption of toxic shellfish as well as a respiratory irritation after inhalation of toxic sea spray. Groundbreaking research, leading to this third potential form of poisoning, identified that metabolism produces chemically reactive forms of the toxin. Recognizing the potential of these metabolites to attack DNA, NOAA scientists analyzed the DNA after the toxin was metabolized in the lung.

Scientists have not yet determined if brevetoxin damaged DNA accurately repairs itself or if gene mutations result. Brevetoxin has been measured in air during red tide events and human exposure levels have been reported; however, the long-term health risk associated with inhalation of brevetoxins remains to be defined. Individuals are continually exposed to environmental chemicals capable of damaging DNA like carcinogens found in tobacco smoke and air pollution. It is possible that exposure to brevetoxins can add to the cumulative amount of chemically altered DNA in the lungs; an indicator of cancer risk.

"This represents a significant breakthrough in defining the metabolic transformation of brevetoxins and the potential long-term health effects of red tides. It should change perceptions of risk and management of inhalation exposure to harmful algal blooms," notes Ramsdell.

Red tides in the Gulf of Mexico are common, and often persistent, naturally occurring events that release toxins into sea spray aerosols. These aerosols are a particular problem at beaches, as they can cause respiratory distress to lifeguards and beachgoers. Although these shorter-term effects of the airborne toxin are well characterized, potential longer-term effects remain a concern to health officials and coastal communities.

Scientists, in NOAA's Oceans and Human Health Initiative, are studying long term health consequences of harmful algal blooms, to predict how the condition of the coastal waters affect human health and how to reduce or eliminate health risks.


Story Source:

The above story is based on materials provided by National Oceanic And Atmospheric Administration. Note: Materials may be edited for content and length.


Cite This Page:

National Oceanic And Atmospheric Administration. "Aerosol Toxins From Red Tides May Cause Long-term Health Threat." ScienceDaily. ScienceDaily, 9 July 2008. <www.sciencedaily.com/releases/2008/07/080709110049.htm>.
National Oceanic And Atmospheric Administration. (2008, July 9). Aerosol Toxins From Red Tides May Cause Long-term Health Threat. ScienceDaily. Retrieved November 26, 2014 from www.sciencedaily.com/releases/2008/07/080709110049.htm
National Oceanic And Atmospheric Administration. "Aerosol Toxins From Red Tides May Cause Long-term Health Threat." ScienceDaily. www.sciencedaily.com/releases/2008/07/080709110049.htm (accessed November 26, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Wednesday, November 26, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

Newsy (Nov. 25, 2014) — The US FDA is announcing new calorie rules on Tuesday that will require everywhere from theaters to vending machines to include calorie counts. Video provided by Newsy
Powered by NewsLook.com
Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Newsy (Nov. 25, 2014) — Need another reason to eat yogurt every day? Researchers now say it could reduce a person's risk of developing type 2 diabetes. Video provided by Newsy
Powered by NewsLook.com
Madagascar Working to Contain Plague Outbreak

Madagascar Working to Contain Plague Outbreak

AFP (Nov. 24, 2014) — Madagascar said Monday it is trying to contain an outbreak of plague -- similar to the Black Death that swept Medieval Europe -- that has killed 40 people and is spreading to the capital Antananarivo. Duration: 00:42 Video provided by AFP
Powered by NewsLook.com
Are Female Bosses More Likely To Be Depressed?

Are Female Bosses More Likely To Be Depressed?

Newsy (Nov. 24, 2014) — A new study links greater authority with increased depressive symptoms among women in the workplace. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins