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Big Cattle: The Genes That Determine Carcass Weight

Date:
August 5, 2009
Source:
BioMed Central
Summary:
An area of chromosome 6 that affects cattle carcass weight has been identified using two different Japanese breeds. Knowledge of this four-gene region should be useful in breeding beef cattle.

An area of chromosome 6 that affects cattle carcass weight has been identified. Knowledge of this four-gene region should be useful in breeding beef cattle.
Credit: iStockphoto/Igotz Ziarreta Barrena

An area of chromosome 6 that affects cattle carcass weight has been identified using two different Japanese breeds. Knowledge of this four-gene region should be useful in breeding beef cattle.

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Akiko Takasuga, from the Shirakawa Institute of Animal Genetics, led a team of researchers who studied Japanese Black and Japanese Brown cattle, two breeds that have survived separately for thousands of years. According to Takasuga, "The 591-kb critical region contains four genes, LOC523874, C6H4orf30, NCAPG, and LOC540095. Interestingly, LOC540095 is the bovine ortholog of the human gene LCORL, and the NCAPG-LCORL region was recently identified as one determinant of human adult height".

The researchers have named the size-determining region CW-2 and have found a single nucleotide polymorphism which can be used as a positional candidate of CW-2 for marker-assisted selection. Takasuga said, "The CW-2 genotype explains a large portion of phenotypic variance. It may be widely distributed among European cattle breeds and not yet be fixed. Selection for this genotype should accelerate the breeding of meatier cattle".


Story Source:

The above story is based on materials provided by BioMed Central. Note: Materials may be edited for content and length.


Journal Reference:

  1. Kouji Setoguchi, Masako Furuta, Takashi Hirano, Tomoko Nagao, Toshio Watanabe, Yoshikazu Sugimoto and Akiko Takasuga. Cross-breed comparisons identified a critical 591-kb region for bovine carcass weight QTL (CW-2) on chromosome 6 and the Ile-442-Met substitution in NCAPG as a positional candidate. BMC Genetics, (in press) [link]

Cite This Page:

BioMed Central. "Big Cattle: The Genes That Determine Carcass Weight." ScienceDaily. ScienceDaily, 5 August 2009. <www.sciencedaily.com/releases/2009/08/090803193649.htm>.
BioMed Central. (2009, August 5). Big Cattle: The Genes That Determine Carcass Weight. ScienceDaily. Retrieved March 5, 2015 from www.sciencedaily.com/releases/2009/08/090803193649.htm
BioMed Central. "Big Cattle: The Genes That Determine Carcass Weight." ScienceDaily. www.sciencedaily.com/releases/2009/08/090803193649.htm (accessed March 5, 2015).

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