Featured Research

from universities, journals, and other organizations

The buzz on fruit flies: New role in the search for addiction treatments

Date:
December 21, 2009
Source:
American Chemical Society
Summary:
Fruit flies may seem like unlikely heroes in the battle against drug abuse, but new research suggests that these insects -- already used to study dozens of human disease -- could claim that role. Scientists are reporting that fruit flies can be used as a simpler and more convenient animal model for studying the effects of cocaine and other drugs of abuse on the brain.

A tiny electrode and pipette inserted into the fruit fly brain make it a simple, convenient model for studying drug abuse in humans.
Credit: American Chemical Society

Fruit flies may seem like unlikely heroes in the battle against drug abuse, but new research suggests that these insects -- already used to study dozens of human disease -- could claim that role. Scientists are reporting that fruit flies can be used as a simpler and more convenient animal model for studying the effects of cocaine and other drugs of abuse on the brain.

Their study appears online in ACS Chemical Neuroscience, a new monthly journal.

Andrew Ewing and colleagues note that laboratory mice, rats, and monkeys have been mainstays in research with the ultimate goal of finding effective medicines for treating addiction. Although these mammals have helped establish the behavioral effects of cocaine on the body, they provide relatively complicated models to study the effects of cocaine and other illicit drugs on the brain and nerves. In the hope for a new simpler animal model they turned to fruit flies, which have many biological similarities to mammals, but are easier to study.

The scientists confirmed those hopes in research that involved giving cocaine, amphetamine, methamphetamine, and methylphenidate to fruit flies and then studying brain chemistry with a microelectrode one-twentieth the diameter of a human hair. The results demonstrate that fruit flies are a valid model for studying drug addiction in humans, the scientists say.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Makos et al. Using in Vivo Electrochemistry To Study the Physiological Effects of Cocaine and Other Stimulants on the Drosophila melanogaster Dopamine Transporter. ACS Chemical Neuroscience, 2009; 091026104139091 DOI: 10.1021/cn900017w

Cite This Page:

American Chemical Society. "The buzz on fruit flies: New role in the search for addiction treatments." ScienceDaily. ScienceDaily, 21 December 2009. <www.sciencedaily.com/releases/2009/12/091202114048.htm>.
American Chemical Society. (2009, December 21). The buzz on fruit flies: New role in the search for addiction treatments. ScienceDaily. Retrieved October 21, 2014 from www.sciencedaily.com/releases/2009/12/091202114048.htm
American Chemical Society. "The buzz on fruit flies: New role in the search for addiction treatments." ScienceDaily. www.sciencedaily.com/releases/2009/12/091202114048.htm (accessed October 21, 2014).

Share This



More Mind & Brain News

Tuesday, October 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

Newsy (Oct. 21, 2014) A medical team has for the first time given a man the ability to walk again after transplanting cells from his brain onto his severed spinal cord. Video provided by Newsy
Powered by NewsLook.com
Portable Breathalyzer Gets You Home Safely

Portable Breathalyzer Gets You Home Safely

Buzz60 (Oct. 21, 2014) Breeze, a portable breathalyzer, gets you home safely by instantly showing your blood alcohol content, and with one tap, lets you call an Uber, a cab or a friend from your contact list to pick you up. Sean Dowling (@SeanDowlingTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Your Birth Season Might Determine Your Temperament

Your Birth Season Might Determine Your Temperament

Newsy (Oct. 20, 2014) A new study says the season you're born in can determine your temperament — and one season has a surprising outcome. Video provided by Newsy
Powered by NewsLook.com
Movies Might Desensitize Violence For Parents, Not Just Kids

Movies Might Desensitize Violence For Parents, Not Just Kids

Newsy (Oct. 20, 2014) A study suggests that parents become desensitized to violent movies as well as children, which leads them to allow their kids to view violent films. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins