Featured Research

from universities, journals, and other organizations

New model predicts environmental effect of pharmaceutical products

Date:
August 26, 2011
Source:
Plataforma SINC
Summary:
Most synthetic chemical products used in consumer goods end up unchanged in the environment. Given the risks this could pose for the environment and human health, researchers in Spain have developed a new tool to effectively predict what will happen to current and future pharmaceutical products.

A wide variety of drugs that can be harmful to wildlife enter the environment.
Credit: SINC

Most synthetic chemical products used in consumer goods end up unchanged in the environment. Given the risks this could pose for the environment and human health, researchers from the Autonomous University of Barcelona (UAB) have developed a new tool to effectively predict what will happen to current and future pharmaceutical products.

Related Articles


Thousands of pharmaceutical products, which are increasingly diverse and increasingly used, are "partially" metabolised by the human body. Those that remain unchanged pass into the waste water treated at sewage plants, which are not always designed to eliminate synthetic organic compounds.

"Sometimes, some substrates can even revert to the original drug within the water treatment plant itself, increasing the concentration of the drug in the effluent discharged, as is the case with carbamazepine (a psychotropic anti-epilepsy drug)," says Xavier Domenech, co-author of the study and a researcher at the Department of Chemistry of the UAB.

The result is that a great variety of drugs that could be harmful to wildlife end up in the environment. "This is of greater concern in the case of water treated for human consumption, in which we are increasingly detecting a cocktail of drugs at low concentrations (nanograms per litre), the long-term effect of which is unknown," explains Domenech.

Pinpointing the effect of a drug

The study, which has been published in Water Air and Soil Pollution, has made it possible to develop a new tool to determine the likelihood of drugs ending up in the environment, and at what concentrations, thereby fulfilling the European Medicines Agency (EMEA) requirement to evaluate the environmental risk of new drugs that are being proposed for marketing.

The new tool, developed by Marc Ribera, lead author of the study, uses some physical-chemical properties of pharmaceuticals and the rate of growth in their use in Spain between 1999 and 2006 to determine how they will behave in the environment. The drugs analysed are those that are most commonly consumed in Spain (more than 1 mg of active substance per person and year), including, among many others, ibuprofen, diazepam, naproxen, omeprazole and paracetamol.

In order to validate the model, the research team compared the model's prediction results on water with values measured by authors in rivers and lakes. "The model used is good at predicting the experimental data, and can be seen as a good predictive model for evaluating the environmental risks of current drugs and those that may be marketed in future," concludes Domenech.


Story Source:

The above story is based on materials provided by Plataforma SINC. Note: Materials may be edited for content and length.


Journal Reference:

  1. Xavier Domθnech, Marc Ribera, Josι Peral. Assessment of Pharmaceuticals Fate in a Model Environment. Water, Air, & Soil Pollution, 2010; 218 (1-4): 413 DOI: 10.1007/s11270-010-0655-y

Cite This Page:

Plataforma SINC. "New model predicts environmental effect of pharmaceutical products." ScienceDaily. ScienceDaily, 26 August 2011. <www.sciencedaily.com/releases/2011/07/110728082302.htm>.
Plataforma SINC. (2011, August 26). New model predicts environmental effect of pharmaceutical products. ScienceDaily. Retrieved December 21, 2014 from www.sciencedaily.com/releases/2011/07/110728082302.htm
Plataforma SINC. "New model predicts environmental effect of pharmaceutical products." ScienceDaily. www.sciencedaily.com/releases/2011/07/110728082302.htm (accessed December 21, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, December 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Best Tips to Curb Holiday Carbs

The Best Tips to Curb Holiday Carbs

Buzz60 (Dec. 19, 2014) — It's hard to resist those delicious but fattening carbs we all crave during the winter months, but there are some ways to stay satisfied without consuming the extra calories. Vanessa Freeman (@VanessaFreeTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Sierra Leone Bikers Spread the Message to Fight Ebola

Sierra Leone Bikers Spread the Message to Fight Ebola

AFP (Dec. 19, 2014) — More than 100 motorcyclists hit the road to spread awareness messages about Ebola. Nearly 7,000 people have now died from the virus, almost all of them in west Africa, according to the World Health Organization. Video provided by AFP
Powered by NewsLook.com
Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) — In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
The Best Protein-Filled Foods to Energize You for the New Year

The Best Protein-Filled Foods to Energize You for the New Year

Buzz60 (Dec. 19, 2014) — The new year is coming and nothing will energize you more for 2015 than protein-filled foods. Fitness and nutrition expert John Basedow (@JohnBasedow) gives his favorite high protein foods that will help you build muscle, lose fat and have endless energy. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins