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Stopping smoking reduces risk of bacterial pneumonia in people with HIV

Date:
January 22, 2013
Source:
BioMed Central Limited
Summary:
Bacterial pneumonia is one of the commonest and most serious infections occurring in people infected with HIV.  A metanalysis of cohort and case control studies finds that current smokers with HIV were at double the risk of bacterial pneumonia than non-smoking counterparts, but that when people stopped smoking their risk was reduced.

Bacterial pneumonia is one of the commonest and most serious infections occurring in people infected with HIV.  A metanalysis of cohort and case control studies published in BioMed Central’s open access journal BMC Medicine finds that current smokers with HIV were at double the risk of bacterial pneumonia than non-smoking counterparts, but that when people stopped smoking their risk was reduced.

The metanalysis reanalysed the data of several thousand participants with HIV, from 14 studies based in USA, Europe and South Africa. Overall it appeared that current smoking was associated with a 70-100% increase in risk of bacterial pneumonia, compared to non-smokers, but that stopping smoking decreased this by about a third. This was independent of CD4 count or antiretroviral therapy.

Prof Paul Aveyard, from University of Oxford who led the study explained that, “Antiretroviral treatment means that people with HIV can have a normal life expectancy. However they still have substantially increased health risks compared to the general population, including risk of pneumonia. Our results show that smokers with HIV have twice the risk of bacterial pneumonia, but that stopping smoking can reduce this risk. In order to prevent this potentially life threatening lung disease we believe that smoking cessation programs should be  promoted as part of HIV treatment.”

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Story Source:

The above story is based on materials provided by BioMed Central Limited. Note: Materials may be edited for content and length.


Journal Reference:

  1. Preeti De, Amanda Farley, Nicola Lindson and Paul Aveyard. Systematic review and meta-analysis: influence of smoking cessation on incidence of pneumonia in HIV. BMC Medicine, 2013 [link]

Cite This Page:

BioMed Central Limited. "Stopping smoking reduces risk of bacterial pneumonia in people with HIV." ScienceDaily. ScienceDaily, 22 January 2013. <www.sciencedaily.com/releases/2013/01/130121192021.htm>.
BioMed Central Limited. (2013, January 22). Stopping smoking reduces risk of bacterial pneumonia in people with HIV. ScienceDaily. Retrieved November 28, 2014 from www.sciencedaily.com/releases/2013/01/130121192021.htm
BioMed Central Limited. "Stopping smoking reduces risk of bacterial pneumonia in people with HIV." ScienceDaily. www.sciencedaily.com/releases/2013/01/130121192021.htm (accessed November 28, 2014).

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