Featured Research

from universities, journals, and other organizations

New insights into conquering influenza

Date:
January 29, 2013
Source:
University of Melbourne
Summary:
Researchers have discovered a new protein that protects against viral infections such as influenza.

Researchers from the University of Melbourne and The Walter and Eliza Hall Institute (WEHI) have discovered a new protein that protects against viral infections such as influenza.

Related Articles


As influenza spreads through the northern hemisphere winter, Dr Linda Wakim and her colleagues in the Laboratory of Professor Jose Villadangos from the Department of Biochemistry and Molecular Biology, and the Department of Microbiology and Immunology, believe they have a new clue to why some people fight infections better than others.

The lab has been investigating the 'defensive devices' contained within the T-cells that are located on exposed body surfaces such as skin and mucosal surfaces to ward off infection. T-cells detect cells infected with viruses and kill them before the virus can reproduce within the infected cell and spread to other cells.

Researchers found these cells contain the protein IFITM3 and this makes them more resistant to viral infections such as Influenza. The findings have been published in Nature Immunology.

"If we learn how to increase the number and longevity of T-cells expressing IFITM3, this could lead to improved vaccines that promote the generation of more resistant T-cells able to provide the greatest protection, for longer." Professor Villadangos said.

Dr Wakim said "We are currently trying to understand why some T-cells and not others express this protective molecule. Probably they encounter some form of chemical signal (a cytokine, or a surface molecule) in the tissues where they lodge, which induces the expression of IFITM3. If we identify these chemical cues, we may be able to include them in future vaccines."


Story Source:

The above story is based on materials provided by University of Melbourne. Note: Materials may be edited for content and length.


Journal Reference:

  1. Linda M Wakim, Nishma Gupta, Justine D Mintern, Jose A Villadangos. Enhanced survival of lung tissue-resident memory CD8 T cells during infection with influenza virus due to selective expression of IFITM3. Nature Immunology, 2013; DOI: 10.1038/ni.2525

Cite This Page:

University of Melbourne. "New insights into conquering influenza." ScienceDaily. ScienceDaily, 29 January 2013. <www.sciencedaily.com/releases/2013/01/130129100243.htm>.
University of Melbourne. (2013, January 29). New insights into conquering influenza. ScienceDaily. Retrieved November 24, 2014 from www.sciencedaily.com/releases/2013/01/130129100243.htm
University of Melbourne. "New insights into conquering influenza." ScienceDaily. www.sciencedaily.com/releases/2013/01/130129100243.htm (accessed November 24, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, November 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Winter Can Cause Depression — Here's How To Combat It

Winter Can Cause Depression — Here's How To Combat It

Newsy (Nov. 23, 2014) Millions of American suffer from seasonal depression every year. It can lead to adverse health effects, but there are ways to ease symptoms. Video provided by Newsy
Powered by NewsLook.com
Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

AFP (Nov. 23, 2014) The arable district of Kenema in Sierra Leone -- at the centre of the Ebola outbreak in May -- has been under quarantine for three months as the cocoa harvest comes in. Duration: 01:32 Video provided by AFP
Powered by NewsLook.com
Don't Fall For Flu Shot Myths

Don't Fall For Flu Shot Myths

Newsy (Nov. 23, 2014) Misconceptions abound when it comes to your annual flu shot. Medical experts say most people older than 6 months should get the shot. Video provided by Newsy
Powered by NewsLook.com
WFP: Ebola Risks Heightened Among Women Throughout Africa

WFP: Ebola Risks Heightened Among Women Throughout Africa

AFP (Nov. 21, 2014) Having children has always been a frightening prospect in Sierra Leone, the world's most dangerous place to give birth, but Ebola has presented an alarming new threat for expectant mothers. Duration: 00:37 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins