Featured Research

from universities, journals, and other organizations

Certain bacteria suppress production of toxic shock toxin: Probiotic potential looms

Date:
March 22, 2013
Source:
American Society for Microbiology
Summary:
Certain Streptococci increase their production of toxic shock syndrome toxin 1, sometimes to potentially dangerous levels, when aerobic bacteria are present in the vagina. But scientists have discovered certain strains of lactobacillus bacteria are capable of dampening production of that toxin.

Certain Streptococci increase their production of toxic shock syndrome toxin 1, sometimes to potentially dangerous levels, when aerobic bacteria are present in the vagina. But scientists from the University of Western Ontario have discovered certain strains of lactobacillus bacteria are capable of dampening production of that toxin according to research published in the journal Applied and Environmental Microbiology.

"The risk of potentially fatal toxic shock syndrome appears to be influenced by the types of bacteria present in the vagina," says principal investigator Gregor Reid.

In planning the study, "I figured that the Staphylococcus aureus strains with the ability to produce toxic shock syndrome toxin might only do this under certain environmental conditions," says Reid. "In the vagina, that means depending on pH and the other bacteria living there."

The researchers took swabs from women with clinically healthy vaginal status, with intermediate status, and from those diagnosed with bacterial vaginosis. They then identified the bacterial species, and assayed for toxic shock syndrome toxin 1. "In particular, Streptococcus agalactiae, often referred to as Group B streptococci, an organism of particular concern when giving birth, increased toxin production 3.7-fold," says Reid. But various species of lactobacillus repressed toxin production, one by 72 percent.

"These experiments emphasize that for proper clinical care of women, we need to know all bacterial types present in the vagina," says Reid. "Culturing is inadequate, and while some microscopy is feasible if the viewer develops the expertise to assess the vaginal smears, rapid 16s sequencing systems are needed as a diagnostic tool," because many species are "very difficult to culture," or have never been cultured.

"We need to vastly improve how we diagnose infections and determine the risk of infection of women," says Reid. He also recommends "improving our ability to manipulate microbiota [with probiotics] in lieu of using broad spectrum antibiotics that were developed 40 years ago, and are not very effective in the vagina, and certainly not designed to neutralize toxins."


Story Source:

The above story is based on materials provided by American Society for Microbiology. Note: Materials may be edited for content and length.


Journal Reference:

  1. R. A. MacPhee, W. L. Miller, G. B. Gloor, J. K. McCormick, J.-A. Hammond, J. P. Burton, G. Reid. Influence of the Vaginal Microbiota on Toxic Shock Syndrome Toxin 1 Production by Staphylococcus aureus. Applied and Environmental Microbiology, 2013; 79 (6): 1835 DOI: 10.1128/AEM.02908-12

Cite This Page:

American Society for Microbiology. "Certain bacteria suppress production of toxic shock toxin: Probiotic potential looms." ScienceDaily. ScienceDaily, 22 March 2013. <www.sciencedaily.com/releases/2013/03/130322125403.htm>.
American Society for Microbiology. (2013, March 22). Certain bacteria suppress production of toxic shock toxin: Probiotic potential looms. ScienceDaily. Retrieved July 31, 2014 from www.sciencedaily.com/releases/2013/03/130322125403.htm
American Society for Microbiology. "Certain bacteria suppress production of toxic shock toxin: Probiotic potential looms." ScienceDaily. www.sciencedaily.com/releases/2013/03/130322125403.htm (accessed July 31, 2014).

Share This




More Plants & Animals News

Thursday, July 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Raw: Thousands Flocking to German Crop Circle

Raw: Thousands Flocking to German Crop Circle

AP (July 30, 2014) Thousands of people are trekking to a Bavarian farmer's field to check out a mysterious set of crop circles. (July 30) Video provided by AP
Powered by NewsLook.com
Concern Grows Over Worsening Ebola Crisis

Concern Grows Over Worsening Ebola Crisis

AFP (July 30, 2014) Pan-African airline ASKY has suspended all flights to and from the capitals of Liberia and Sierra Leone amid the worsening Ebola health crisis, which has so far caused 672 deaths in Guinea, Liberia and Sierra Leone. Duration: 00:43 Video provided by AFP
Powered by NewsLook.com
At Least 20 Chikungunya Cases in New Jersey

At Least 20 Chikungunya Cases in New Jersey

AP (July 30, 2014) At least 20 New Jersey residents have tested positive for chikungunya, a mosquito-borne virus that has spread through the Caribbean. (July 30) Video provided by AP
Powered by NewsLook.com
Xtreme Eating: Your Daily Caloric Intake All On One Plate

Xtreme Eating: Your Daily Caloric Intake All On One Plate

Newsy (July 30, 2014) The Center for Science in the Public Interest released its 2014 list of single meals with whopping calorie counts. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

    Technology News



      Save/Print:
      Share:

      Free Subscriptions


      Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

      Get Social & Mobile


      Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

      Have Feedback?


      Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
      Mobile: iPhone Android Web
      Follow: Facebook Twitter Google+
      Subscribe: RSS Feeds Email Newsletters
      Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins