Featured Research

from universities, journals, and other organizations

Sunlight adaptation region of Neanderthal genome found in up to 65 percent of modern East Asian population

Date:
December 18, 2013
Source:
Molecular Biology and Evolution (Oxford University Press)
Summary:
With the Neanderthal genome now published, for the first time, scientists have a rich new resource of comparative evolution. For example, recently, scientists have shown that humans and Neanderthals once interbred, with the accumulation of elements of Neanderthal DNA found in up to 5 percent in modern humans. Scientist have found evidence of accumulation of a Neanderthal DNA region found on chromosome 3 that contains 18 genes, with several related to UV-light adaptation, including the Hyal2 gene. Their results reveal this region was positively selected and enriched in East Asians, ranging from up to 49 percent in Japanese to 66 percent in Southern Chinese.

Scientist have found evidence of accumulation of a Neanderthal DNA region found on chromosome 3 that contains 18 genes, with several related to UV-light adaptation. Their results reveal this region was positively selected and enriched in East Asians, ranging from up to 49 percent in Japanese to 66 percent in Southern Chinese.
Credit: BRAD / Fotolia

With the Neanderthal genome now published, for the first time, scientists have a rich new resource of comparative evolution. For example, recently, scientists have shown that humans and Neanderthals once interbred, with the accumulation of elements of Neanderthal DNA found in up to 5 percent in modern humans.

Are there any advantages to the retention of Neanderthal DNA that favors modern humans? In a new article published in Molecular Biology and Evolution, authors Jin, et. al., present evidence for the accumulation of a Neanderthal DNA region found on chromosome 3 that contains 18 genes, with several related to UV-light adaptation, including the Hyal2 gene. Their results reveal this region was positively selected and enriched in East Asians, ranging from up to 49 percent in Japanese to 66 percent in Southern Chinese.

Interestingly, the authors note, the geographic distribution of the Neanderthal genomic region suggests that UV-light mutations were shown to be lost during the exodus of modern human from Africa, and reintroduced to Eurasians from Neanderthals. "Overall, it is still very controversial whether there is more Neanderthal DNA contributions to Asians than Europeans, as we have evidence to argue against this," said Lin. "Although in the case of the Hyal2 variant, it did indeed have a higher frequency in Asians."

From 45,000 years to 5,000 years before present, effective population sizes of the Neanderthal region increased at a steady rate. Notably, the growth rate of the effective population size increased at around 5,000 to 3,500 years before present, which suggests a population expansion event. This Asian-specific Neanderthal evolutionary event is also consistent with previous reports of higher levels of Neanderthal ancestry in East Asians than in Europeans.


Story Source:

The above story is based on materials provided by Molecular Biology and Evolution (Oxford University Press). Note: Materials may be edited for content and length.


Journal Reference:

  1. Q. Ding, Y. Hu, S. Xu, J. Wang, L. Jin. Neanderthal Introgression at Chromosome 3p21.31 was Under Positive Natural Selection in East Asians. Molecular Biology and Evolution, 2013; DOI: 10.1093/molbev/mst260

Cite This Page:

Molecular Biology and Evolution (Oxford University Press). "Sunlight adaptation region of Neanderthal genome found in up to 65 percent of modern East Asian population." ScienceDaily. ScienceDaily, 18 December 2013. <www.sciencedaily.com/releases/2013/12/131218100229.htm>.
Molecular Biology and Evolution (Oxford University Press). (2013, December 18). Sunlight adaptation region of Neanderthal genome found in up to 65 percent of modern East Asian population. ScienceDaily. Retrieved April 21, 2014 from www.sciencedaily.com/releases/2013/12/131218100229.htm
Molecular Biology and Evolution (Oxford University Press). "Sunlight adaptation region of Neanderthal genome found in up to 65 percent of modern East Asian population." ScienceDaily. www.sciencedaily.com/releases/2013/12/131218100229.htm (accessed April 21, 2014).

Share This



More Fossils & Ruins News

Monday, April 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Mich. Boy Unearths 10,000-Year-Old Mastodon Tooth

Mich. Boy Unearths 10,000-Year-Old Mastodon Tooth

Newsy (Apr. 20, 2014) A 9-year-old Michigan boy was exploring a creek when he came across a 10,000-year-old tooth from a prehistoric mastodon. Video provided by Newsy
Powered by NewsLook.com
Couple Finds Love Letters From WWI In Attic

Couple Finds Love Letters From WWI In Attic

Newsy (Apr. 17, 2014) A couple found love letters from World War I in their attic. They were able to deliver them to relatives of the writer of those letters. Video provided by Newsy
Powered by NewsLook.com
Erotic Art Offers Glimpse of China's 'lost' Sexual Philosophy

Erotic Art Offers Glimpse of China's 'lost' Sexual Philosophy

AFP (Apr. 16, 2014) Explicit Chinese art works dating back centuries go on display in Hong Kong, revealing China's ancient relationship with sex. Video provided by AFP
Powered by NewsLook.com
French Historians Fight to Save Iconic La Samaritaine Buildings

French Historians Fight to Save Iconic La Samaritaine Buildings

AFP (Apr. 15, 2014) Parisians and local historians are fighting to save one of the French capital's iconic buildings, the La Samaritaine department store. Duration: 01:42 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins