An international team of health researchers says that the number one research priority for reducing childhood deaths from diarrhoea is to find ways to improve the acceptability and effectiveness of oral rehydration solution (ORS).
But unfortunately, says the team, donor agencies have shown little interest in funding this type of research.
Childhood diarrhoea claims almost 2 million lives each year and is responsible for about 1 in 5 child deaths worldwide. The World Health Organization (WHO) recommends a new reduced osmolarity ORS for treating dehydrating diarrhoeal disease.
The 15 researchers, led by Olivier Fontaine at the WHO's Department of Child and Adolescent Health and Development, set out to define which research questions should be prioritized to improve the chances of cutting childhood diarrhoea deaths by 2015. They used a methodology designed by the Child Health and Nutrition Research Initiative (http://www.chnri.org) — in which all possible research options are initially listed and are then given scores.
The top 10% of research investments prioritized by the researchers included:
"The main message of the process," say Fontaine and colleagues, "is that the research priorities to reduce global mortality from childhood diarrhoea within the present context are dominated by health systems, policy research, and epidemiological questions."
"These questions are mainly targeted at better understanding the barriers towards implementation, effectiveness, and optimisation of use of available interventions and programmes such as oral rehydration solution, zinc supplementation, exclusive breastfeeding, and Integrated Management of Childhood Illness."
The authors caution, however, that "very few donors agencies recognise the importance of these domains of health research and are willing to readily invest in those options."
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