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Critical to screen patients with rheumatoid arthritis for hearing impairment

Date:
April 22, 2016
Source:
Bentham Science Publishers
Summary:
The objective of a new review is to evaluate published clinical reports related to hearing impairment in patients with RA. Furthermore, researchers discuss possible pathologies and associated factors as well as new treatment modalities.
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Rheumatoid arthritis (RA) is the most common autoimmune arthritis, affecting 1% of the general population. Despite its main articular manifestations, RA caninvolveextra-articular organs including the auditory system.

HI in RA is multifactorial. Mechanism of injury and predisposing factors are not clearly understood. Sensorineural hearing loss is the most common type in RA patients with a prevalence of 25-72%. Possible pathologies are including: Synovial destruction of incudostapedial and incudomalleolar joints, rheumatoid nodules, auditory neuropathy, destruction of the cochlear hair cells and drug-induced ototoxicity. "Elderly Patients and those with long disease duration, active disease, seropositivity, elevatedacute phase reactants and rheumatoid nodules are more likely to have HI," demonstrated a recent study by Amir Emamifar, Kristine Bjørndal and Inger Marie Jensen Hansen.

Environmental factors for instance smoking, alcohol and noise can deteriorate the condition. Passive smokers are also at risk of HI. Long-term exposure to alcohol affects hearing in RA, causing harmful effects on the cochlear function.

Results of pure tone audiometry revealed that RA patients have high prevalence of HI for all frequencies.Transiently Evoked Otoacoustic Emissions (TEOAEs) test has been used widely to evaluate cochlear function, and is capable of detecting various amounts of decreases in RA patients at an early stage of the disease.

Treatment of HI in RA is empirical. Oral steroids and intensifying Disease-Modifying Antirheumatic Drugs might be an option. Anti-oxidants (eg. vitamin E) may play a protective role for the inner ear. Regular audiometric test and TEOAEs should be performed. Patients will also benefit from the cessation of smoking and alcohol. Like other causes of HI in healthy individuals, HI in RA can also be managed by use of different types of hearing aids and implantable devices.


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Materials provided by Bentham Science Publishers. Note: Content may be edited for style and length.


Journal Reference:

  1. Amir Emamifar, Kristine Bjoerndal, Inger M.J. Hansen. Is Hearing Impairment Associated with Rheumatoid Arthritis? A Review. The Open Rheumatology Journal, 2016; 10 (1): 26 DOI: 10.2174/1874312901610010026

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Bentham Science Publishers. "Critical to screen patients with rheumatoid arthritis for hearing impairment." ScienceDaily. ScienceDaily, 22 April 2016. <www.sciencedaily.com/releases/2016/04/160422115526.htm>.
Bentham Science Publishers. (2016, April 22). Critical to screen patients with rheumatoid arthritis for hearing impairment. ScienceDaily. Retrieved May 27, 2017 from www.sciencedaily.com/releases/2016/04/160422115526.htm
Bentham Science Publishers. "Critical to screen patients with rheumatoid arthritis for hearing impairment." ScienceDaily. www.sciencedaily.com/releases/2016/04/160422115526.htm (accessed May 27, 2017).

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