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33,000 people die every year due to infections with antibiotic-resistant bacteria

Date:
November 6, 2018
Source:
European Centre for Disease Prevention and Control (ECDC)
Summary:
An new study estimates the burden of five types of infections caused by antibiotic-resistant bacteria of public health concern in the European Union and in the European Economic Area (EU/EEA). The burden of disease is measured in number of cases, attributable deaths and disability-adjusted life years (DALYs). These estimates are based on data from the European Antimicrobial Resistance Surveillance Network (EARS-Net) data from 2015.
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FULL STORY

An ECDC study estimates the burden of five types of infections caused by antibiotic-resistant bacteria of public health concern in the European Union and in the European Economic Area (EU/EEA). The burden of disease is measured in number of cases, attributable deaths and disability-adjusted life years (DALYs). These estimates are based on data from the European Antimicrobial Resistance Surveillance Network (EARS-Net) data from 2015.

The authors said "the estimated burden of infections with antibiotic-resistant bacteria in the EU/EEA is substantial compared to that of other infectious diseases, and increased since 2007. Strategies to prevent and control antibiotic-resistant bacteria require coordination at EU/EEA and global level. However, our study showed that the contribution of various antibiotic-resistant bacteria to the overall burden varies greatly between countries, thus highlighting the need for prevention and control strategies tailored to the need of each EU/EEA country."

The study estimates that about 33000 people die each year as a direct consequence of an infection due to bacteria resistant to antibiotics and that the burden of these infections is comparable to that of influenza, tuberculosis and HIV/AIDS combined. It also explains that 75% of the burden of disease is due to healthcare-associated infections (HAIs) and that reducing this through adequate infection prevention and control measures, as well as antibiotic stewardship, could be an achievable goal in healthcare settings.

Finally, the study shows that 39% of the burden is caused by infections with bacteria resistant to last-line antibiotics such as carbapenems and colistin. This is an increase from 2007 and is worrying because these antibiotics are the last treatment options available. When these are no longer effective, it is extremely difficult or, in many cases, impossible to treat infections.


Story Source:

Materials provided by European Centre for Disease Prevention and Control (ECDC). Note: Content may be edited for style and length.


Journal Reference:

  1. Alessandro Cassini, Liselotte Diaz Högberg, Diamantis Plachouras, Annalisa Quattrocchi, Ana Hoxha, Gunnar Skov Simonsen, Mélanie Colomb-Cotinat, Mirjam E Kretzschmar, Brecht Devleesschauwer, Michele Cecchini, Driss Ait Ouakrim, Tiago Cravo Oliveira, Marc J Struelens, Carl Suetens, Dominique L Monnet, Reinhild Strauss, Karl Mertens, Thomas Struyf, Boudewijn Catry, Katrien Latour, Ivan N Ivanov, Elina G Dobreva, Arjana Tambic Andraševic, Silvija Soprek, Ana Budimir, Niki Paphitou, Helena Žemlicková, Stefan Schytte Olsen, Ute Wolff Sönksen, Pille Märtin, Marina Ivanova, Outi Lyytikäinen, Jari Jalava, Bruno Coignard, Tim Eckmanns, Muna Abu Sin, Sebastian Haller, George L Daikos, Achilleas Gikas, Sotirios Tsiodras, Flora Kontopidou, Ákos Tóth, Ágnes Hajdu, Ólafur Guólaugsson, Karl G Kristinsson, Stephen Murchan, Karen Burns, Patrizio Pezzotti, Carlo Gagliotti, Uga Dumpis, Agne Liuimiene, Monique Perrin, Michael A Borg, Sabine C de Greeff, Jos CM Monen, Mayke BG Koek, Petter Elstrøm, Dorota Zabicka, Aleksander Deptula, Waleria Hryniewicz, Manuela Caniça, Paulo Jorge Nogueira, Paulo André Fernandes, Vera Manageiro, Gabriel A Popescu, Roxana I Serban, Eva Schréterová, Slavka Litvová, Mária Štefkovicová, Jana Kolman, Irena Klavs, Aleš Korošec, Belén Aracil, Angel Asensio, María Pérez-Vázquez, Hanna Billström, Sofie Larsson, Jacqui S Reilly, Alan Johnson, Susan Hopkins. Attributable deaths and disability-adjusted life-years caused by infections with antibiotic-resistant bacteria in the EU and the European Economic Area in 2015: a population-level modelling analysis. The Lancet Infectious Diseases, 2018; DOI: 10.1016/S1473-3099(18)30605-4

Cite This Page:

European Centre for Disease Prevention and Control (ECDC). "33,000 people die every year due to infections with antibiotic-resistant bacteria." ScienceDaily. ScienceDaily, 6 November 2018. <www.sciencedaily.com/releases/2018/11/181106104213.htm>.
European Centre for Disease Prevention and Control (ECDC). (2018, November 6). 33,000 people die every year due to infections with antibiotic-resistant bacteria. ScienceDaily. Retrieved February 25, 2024 from www.sciencedaily.com/releases/2018/11/181106104213.htm
European Centre for Disease Prevention and Control (ECDC). "33,000 people die every year due to infections with antibiotic-resistant bacteria." ScienceDaily. www.sciencedaily.com/releases/2018/11/181106104213.htm (accessed February 25, 2024).

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