Tuberculosis News

December 3, 2023

Top Headlines

A New Dawn in the Fight Against Tuberculosis

Nov. 8, 2023 — Medical researchers are striving to fast-track the development of innovative Tuberculosis (TB) treatments. They have announced the start of a phase 2B/C clinical trial program. The announcement is a major milestone for the project and the TB ...

How Cord-Like Aggregates of Bacteria Lead to Tuberculosis Infections

Oct. 20, 2023 — The ability of Mycobacterium tuberculosis (MTB), a serious respiratory infection, to form snake-like cords was first noted nearly 80 years ago. Investigators report the biophysical mechanisms by which these cords form and demonstrate how several ...

New Discovery May 'Unlock' the Future of Infectious Disease and Cancer Treatment

Oct. 5, 2023 — Researchers have identified a 'guard mechanism' for a protein which attacks microbes in infected cells, opening the possibility of new treatments for Toxoplasma, Chlamydia, Tuberculosis and even ...

Study Demonstrates Efficacy of New Short-Term Resistant TB Treatment

July 31, 2023 — Tuberculosis (TB) disproportionately affects vulnerable populations including those with limited economic resources, HIV patients, those whose diet is deficient in nutrients and others. Resistant TB (MDR TB) does not respond to first line ...

Latest Headlines

updated 10:58pm EST

Multi-Drug Resistant Strain of E. Coli Battles Bacteria in Healthy Gut

Oct. 17, 2023 — Different strains of E. coli can outcompete one another to take over the gut, a new study ...

TB Vaccine Discovery Paves Path to End Number One Killer of People Living With HIV

Oct. 10, 2023 — Scientists have discovered a tuberculosis (TB) vaccination strategy that could prevent the leading cause of death among people worldwide living with ...

Tuberculosis Disease Intensifies HIV Antibody Response in People With HIV

May 9, 2023 — New research found that people living with HIV that have had pulmonary tuberculosis had broader and more potent HIV antibody responses and differences in HIV sequences predicted to be antibody ...

Testing Antibiotic Resistance With a Fast, Cheap, and Easy Method

Apr. 24, 2023 — Researchers have developed a novel and highly efficient method for rapid antibiotic susceptibility testing using optical microscopy. The technique, called Optical Nanomotion Detection, is extremely ...

Harnessing Power of Immune System May Lessen Reliance on Antibiotics for Infections Like TB

Mar. 23, 2023 — Researchers have found that the body's process of removing old and damaged cell parts, is also an essential part of tackling infections that take ...

Researchers Develop New Technology to Easily Detect Active TB

Mar. 13, 2023 — A team of faculty has discovered new technology that will quickly and easily detect active Mycobacterium tuberculosis (TB) infection ...

In Search of Inflammatory Achilles Heel

Mar. 9, 2023 — Neutrophils induce anti-inflammatory -- or M2 -- macrophages deep in their granulocyte core. The dense globular structures of granulomas in animals, particularly in the lungs, have been studied. ...

Catching the Wrongdoers in the Act: Chemists Develop a Novel Tool to Decipher Bacterial Infections in Real Time

Jan. 31, 2023 — A research team has developed a novel chemical tool to reveal how bacteria adapt to the host environment and control host cells. This tool can be ...

Study Shows FDA-Approved TB Regimen May Not Work Against the Deadliest Form of TB Due to Multidrug-Resistant Strains

Jan. 27, 2023 — Findings in animal models show that a U.S. Food and Drug Administration (FDA)-approved antibiotic regimen for multidrug-resistant (MDR) tuberculosis ...

Developing Antibiotics That Target Multiple-Drug-Resistant Bacteria

Dec. 20, 2022 — Researchers have designed and synthesized analogs of a new antibiotic that is effective against multidrug-resistant bacteria, opening a new front in the fight against these ...

Earlier Headlines

Summaries
Headlines

Detecting Rapidly Mutating Bacteria and Viruses With AutoPLP

Feb. 15, 2023 — The microbes responsible for some infections can rapidly mutate into variants that evade detection and treatment. Now, a newly developed procedure could help researchers catch up to these sneaky ...

New DNA Analysis Provides Accurate Tuberculosis Genome

Dec. 16, 2022 — Researchers hope their genome-assembly tool will spur the development of new treatments for bacterial ...

Immunologic Defect May Leave Some Vulnerable to Rare Bacterial Infection

Oct. 3, 2022 — The bacterium that causes tuberculosis has a cousin you've never heard of: MAC. This bacterial complex is everywhere, but most people never show symptoms. Yet some people get very, very sick. ...

Using Artificial Intelligence to Improve Tuberculosis Treatments

Sep. 14, 2022 — Researchers used data from large studies that contained laboratory measurements of two-drug combinations of 12 anti-tuberculosis drugs. Using mathematical models, the team discovered a set of rules ...

Manuka Honey Could Help Clear Deadly Drug-Resistant Lung Infection, Research Finds

Sep. 8, 2022 — A potential new treatment combining natural manuka honey with a widely used drug has been developed by scientists to treat a potentially lethal lung infection and greatly reduce side effects of one ...

Modified Bladder Cancer Treatment Shows Promise in Animal Studies

Aug. 22, 2022 — Many bladder cancer patients cannot tolerate the strong side effects of the gold standard treatment. Researchers have found a way to minimize those side effects and are poised to move into clinical ...

Multiple Shots of the BCG Vaccine Protect Type 1 Diabetics from COVID-19, Study Finds

Aug. 15, 2022 — Researchers are hoping the results of a new study will spur a larger scale study of the effects of the BCG vaccine in patients with type 1 diabetes, considered among the most vulnerable groups to ...

New Antibiotic Resistance Genes Identified in Tuberculosis

Aug. 11, 2022 — An international consortium analyzed the genetic sequences and antibiotic susceptibility of more than 10,000 global Mycobacterium tuberculosis ...

BCG Vaccine Prevents Tuberculosis in Young Children, but Not Adults

Aug. 9, 2022 — Amid debate on the effectiveness of the tuberculosis vaccine, a new study suggests that the vaccine is protective against TB in children under 5, but adolescents and adults in high-burden countries ...

Scientists Create Long-Acting Injectable Drug Delivery System for Tuberculosis

Aug. 8, 2022 — Research in animal models showed the potential of delivering a TB drug with one injection that lasts at least four months, in lieu of the current standard treatment requiring constant adherence to a ...

Tuberculosis Vaccine Passes Safety Test: Study

Aug. 2, 2022 — The vaccine candidate VPM1002 shows its safety in a study with HIV- and non-HIV-exposed ...

Discovering New Treatments for Tuberculosis

July 21, 2022 — Mycobacterium tuberculosis, the causative agent of tuberculosis, remains the leading cause of infectious disease worldwide, affecting approximately a quarter of the globe's population. Treatment ...

TB Treatment During Pregnancy Is Safe for Mom and Baby, Study Suggests

June 22, 2022 — Seven out of 10 pregnant women were cured of their multidrug-resistant tuberculosis and delivered healthy babies after taking a medication that had previously been considered unsafe in pregnancy, a ...

Genetic Mutations Enable Efficient Evolution of TB-Causing Bacteria

June 21, 2022 — Researchers have identified how the bacterium that causes tuberculosis (TB) can evolve rapidly in response to new ...

New Blood Test Can Help Doctors Diagnose Tuberculosis and Monitor Treatment

June 1, 2022 — Researchers have developed a new highly sensitive blood test for tuberculosis (TB) that screens for DNA fragments of the Mycobacterium tuberculosis bacteria that causes the deadly ...

New Antibiotics Could Tackle Drug-Resistant Tuberculosis Bacteria

May 31, 2022 — According to a new study, a new class of antibiotics is highly effective against drug-resistant tuberculosis. If validated in clinical trials, the new drug class would represent a major advance in ...

New Insights Into Antibiotic Resistance

May 25, 2022 — Treatment of severe infections caused by pathogenic bacteria relies on 'last resort' antibiotics, but rising resistance by 'superbugs' to most clinically approved drugs leaves ...

Researchers Identify Rare Genetic Markers of Drug-Resistant Tuberculosis

May 9, 2022 — Researchers have identified rare genetic markers in M. tuberculosis that could improve early detection of drug-resistant strains of the disease, helping prevent their ...

New Details Behind the Body's Response to Tuberculosis Could Lead to a More Effective Vaccine

Apr. 27, 2022 — In a person with active tuberculosis, immune activity can promote bacterial clearance, but in some situations, bacteria persist and grow. New research in an animal model of tuberculosis reveals which ...

Molecular Tests for TB

Apr. 26, 2022 — A potential game-changer in the tuberculosis epidemic was how the tuberculosis community viewed rapid molecular tests for tuberculosis and tuberculosis drug resistance. This was 12 years ago, with ...

Wednesday, February 15, 2023