New! Sign up for our free email newsletter.
Science News
from research organizations

Social, environmental factors may raise risk of developing heart disease and stroke

March 27, 2024
American Heart Association
Neighborhoods with more adversity have up to twice the increased risk of heart disease and stroke, according to a new study.

People who live in areas with social and environmental adversities may have up to twice the increased risk for developing heart disease and stroke, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

In this study, environmental adversities included air and water pollution, potentially hazardous or toxic sites, few recreational parks, and high traffic roads, railways or airports. Social vulnerabilities were defined as racial and ethnic minority status; socioeconomic factors such as income, education and employment levels; housing status; and access to internet and health care.

"Our study is one of the first to examine the impact of both social and environmental factors in combination and looked at the complex interplay between them," said the study's senior author Sarju Ganatra, M.D., a cardiologist and vice chair in the department of medicine for research and director of the Cardio-Oncology Program and South Asian Cardio-Metabolic Program at Lahey Hospital and Medical Center in Burlington, Massachusetts.

This study used the Environmental Justice Index -- developed with data from the U.S. Census Bureau, the U.S. Environmental Protection Agency, U.S. Mine Safety and Health Administration and the U.S. Centers for Disease Control and Prevention -- to rate environmental disadvantages across all U.S. census tracts.

The analysis found:

  • People living in the most environmentally vulnerable neighborhoods had 1.6 times the rate of blocked arteries and more than twice the rate of stroke compared to people living in the least environmentally vulnerable neighborhoods.
  • Cardiovascular disease risk factors were higher in the most vulnerable areas with twice the rate of Type 2 diabetes, 1.8 times higher rates of chronic kidney disease, and 1.5 times higher incidence of high blood pressure and obesity.
  • About 30% of all U.S. residents aged 18-44, 21% of Black adults and most Hispanic adults resided in places with alarmingly high environmental burdens.

"I was amazed to see the tight links and complex interplay between social and environmental factors on health outcomes. We were able to demonstrate their 'dual hit' on health outcomes. And beyond that, we were more amazed by the fact that even after adjusting for socioeconomic factors, environmental factors played a crucial and independent role in determining various heart disease and other related health outcomes," Ganatra said.

According to researchers, reversing the impact of social and environmental disadvantages will require a multi-pronged approach with interventions to reduce pollution exposure and policies that address the causes of poverty, urban revitalization, high quality public education, job creation programs and affordable housing, along with steps to ensure universal access to quality health care.

"Our aim is to empower the health care community to better inform patients about environmental factors they encounter daily. Patients, in turn, gain the ability to reduce their exposure to harmful environmental conditions, such as exposure to harmful chemicals and air pollutants to minimize health hazards and mitigate health risks," Ganatra said.

Story Source:

Materials provided by American Heart Association. Note: Content may be edited for style and length.

Journal Reference:

  1. Sumanth Khadke, Ashish Kumar, Sadeer Al‐Kindi, Sanjay Rajagopalan, Yixin Kong, Khurram Nasir, Javaria Ahmad, Gary Adamkiewicz, Scott Delaney, Anju Nohria, Sourbha S. Dani, Sarju Ganatra. Association of Environmental Injustice and Cardiovascular Diseases and Risk Factors in the United States. Journal of the American Heart Association, 2024; DOI: 10.1161/JAHA.123.033428

Cite This Page:

American Heart Association. "Social, environmental factors may raise risk of developing heart disease and stroke." ScienceDaily. ScienceDaily, 27 March 2024. <>.
American Heart Association. (2024, March 27). Social, environmental factors may raise risk of developing heart disease and stroke. ScienceDaily. Retrieved April 24, 2024 from
American Heart Association. "Social, environmental factors may raise risk of developing heart disease and stroke." ScienceDaily. (accessed April 24, 2024).

Explore More

from ScienceDaily