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COX-2 inhibitor
COX-2 selective inhibitor is a form of Non-steroidal anti-inflammatory drug (NSAID) that directly targets COX-2, an enzyme responsible for inflammation and pain. Selectivity for COX-2 reduces the risk of peptic ulceration, and is the main feature of celecoxib, rofecoxib and other members of this drug class. Cox-2-selectivity does not seem to affect other side-effects of NSAIDs (most notably an increased risk of renal failure), and some results have aroused the suspicion that there might be an increase in the risk for heart attack, thrombosis and stroke by a relative increase in thromboxane. Rofecoxib was taken off the market in 2004 because of these concerns.
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Health & Medicine News
August 21, 2025
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Aug. 20, 2025 — Scientists have uncovered a hidden weakness in one of the deadliest childhood cancers. The tumors, which spread quickly and are notoriously hard to treat, rely on a sugar-processing pathway to survive and grow. By blocking this pathway, researchers ...
Aug. 19, 2025 — MSU researchers discovered that microbes begin shaping the brain while still in the womb, influencing neurons in a region critical for stress and social behavior. Their findings suggest modern birth practices that alter the microbiome may have ...
Aug. 19, 2025 — A rare immune disorder has inspired a potential universal antiviral therapy. By mimicking the mutation s unique inflammation signature, researchers developed an mRNA-based treatment that stopped influenza and COVID-19 in animal ...
Aug. 19, 2025 — A breakthrough mRNA cancer vaccine has shown the ability to supercharge the effects of immunotherapy in mice, sparking hope for a universal “off-the-shelf” treatment that could fight multiple cancers. Unlike traditional vaccines designed to ...
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Aug. 18, 2025 — Researchers discovered that Covid accelerates blood vessel aging by about five years, especially in women. Even mild infections increased arterial stiffness, with vaccinated individuals showing less damage. This vascular aging may raise long-term ...
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Aug. 17, 2025 — Scientists have engineered a groundbreaking cancer treatment that uses bacteria to smuggle viruses directly into tumors, bypassing the immune system and delivering a powerful one-two punch against ...
Aug. 16, 2025 — A groundbreaking study has found that a simple change in walking style can ease osteoarthritis pain as effectively as medication—without the side effects. By adjusting foot angle, participants ...
Aug. 15, 2025 — Arizona State University scientists have unveiled NasRED, a revolutionary one-drop blood test that can detect diseases like COVID-19, Ebola, HIV, and Lyme with incredible speed and precision. Using ...
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