Reference Terms
from Wikipedia, the free encyclopedia
Coeliac disease
Coeliac disease or celiac disease is an autoimmune disorder of the small bowel that occurs in genetically predisposed individuals in all age groups after early infancy. Symptoms may include diarrhoea, failure to thrive (in children) and fatigue, but these may be absent and associated symptoms in all other organ systems have been described. It affects approximately 1% of Caucasian populations, though it is significantly underdiagnosed. A growing portion of diagnoses are being made in asymptomatic persons as a result of increasing screening.
Coeliac disease is caused by an abnormal reaction to gliadin, a gluten protein found in wheat (and similar proteins of the tribe Triticeae which includes other cultivars such as barley and rye). Upon exposure to gliadin, the body's immune system cross-reacts with the enzyme tissue transglutaminase, causing an inflammatory reaction that leads to flattening of the lining of the small intestine, which interferes with the absorption of nutrients. The only effective treatment is a diet, lifelong in principle, from which gluten is absent.
Related Stories
1
2
Health & Medicine News
June 9, 2025
June 9, 2025 — A breakthrough study from Keck Medicine of USC may have found a powerful new triple therapy for glioblastoma, one of the deadliest brain cancers. By combining Tumor Treating Fields (TTFields), which ...
June 9, 2025 — Teens are diving into intense skincare routines inspired by TikTok, often slathering on six or more products daily, sometimes over ten in just minutes, chasing beauty ideals that favor lighter, flawless skin. But new research warns this digital ...
June 9, 2025 — A new Rutgers Health study reveals a surprising twist in the antibiotic resistance story: instead of simply killing bacteria, drugs like ciprofloxacin can actually trigger a kind of microbial survival mode. By crashing the bacteria's energy levels, ...
June 9, 2025 — A rare genetic disorder called Werner syndrome causes premature aging and devastating health complications from an early age, yet treatment options have been lacking. New hope emerges from Chiba University, where researchers conducted the first ...
June 9, 2025 — A revolutionary STI test developed by UK-based Linear Diagnostics is on track to dramatically reduce the time it takes to detect infections like gonorrhea and chlamydia. Built on ultra-fast EXPAR DNA amplification technology, the platform can ...
June 8, 2025 — Genetic research in Sweden has unveiled three new gene variants that dramatically increase the risk of venous blood clots, sometimes by up to 180%. These discoveries build on existing knowledge of Factor V Leiden and suggest that genetics plays a ...
June 7, 2025 — Cannabis use among older Americans has climbed dramatically, with 7% of adults 65 and older now reporting recent use. This rise isn't just in numbers but also in diversity older users today are more likely to be women, college-educated, and ...
June 7, 2025 — A powerful new discovery reveals that Nup98 a protein once thought to only ferry molecules through the nucleus plays a vital role in safeguarding the most vulnerable areas of DNA. By forming droplet-like 'bubbles' around damaged DNA within dense ...
June 7, 2025 — New research reveals a surprising downside to calorie-cutting diets: a link to higher levels of depressive symptoms, especially in men and those who are overweight. Despite popular beliefs that healthy eating boosts mental wellness, real-life ...
June 6, 2025 — A diabetes drug may soon double as a treatment for liver disease. Dapagliflozin, an SGLT-2 inhibitor typically used for type 2 diabetes, significantly improved liver inflammation and scarring in patients with metabolic dysfunction-associated ...
June 3, 2025 — A new type of mRNA vaccine is more scalable and adaptable to continuously evolving viruses such as SARS-CoV-2 and H5N1, according to a new ...
June 3, 2025 — Using a newly devised, three-dimensional model to study the regeneration of nerve tissue in the nose, researchers have discovered that one type of stem cell thought to be dormant may play a more significant role in preserving the sense of smell than ...
Latest Headlines
updated 12:56 pm ET
June 2, 2025 — A trial of an interactive game that trains people to alter their brain waves has shown promise as a treatment for nerve pain -- offering hope for a new generation of drug-free ...
June 2, 2025 — Researchers have synthesized a new compound called infuzide that shows activity against resistant strains of ...
June 3, 2025 — To satisfy the seafood needs of billions of people, offering them access to a more biodiverse array of fish creates opportunities to mix-and-match ...
June 3, 2025 — A new study found exposure to specific tiny particles in air pollution during pregnancy are associated with increased risk of various negative birth ...
June 3, 2025 — Scientists have discovered how pancreatic cancer cells thrive in the lungs or liver, environments that are as distinct to cells as the ocean and desert are to animals. The spread of cancer cells to ...
June 3, 2025 — According to a recent study, in patients with frontotemporal dementia (FTD), epileptic seizures are significantly more common than previously known. ...
June 3, 2025 — Eating a colorful variety of flavonoid-rich foods like tea, berries, dark chocolate, and apples may significantly lower your risk of chronic diseases ...
June 3, 2025 — Researchers asked patients, some of whom had experienced lower back pain for up to 40 years, if being in nature helped them coped better with their ...
June 3, 2025 — The biosynthesis of the great variety of natural plant products has not yet been elucidated for many medically interesting substances. In a new ...
June 3, 2025 — As psychedelics gain traction as potential treatments for mental health disorders, an international study stands to improve the rigor and reliability of clinical ...