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Rofecoxib

Rofecoxib is a nonsteroidal anti-inflammatory drug that was used in the treatment of osteoarthritis, acute pain conditions, and dysmenorrhoea.

Note: The above text is excerpted from the Wikipedia article "Rofecoxib", which has been released under the GNU Free Documentation License.

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Common Drug Can Improve Hand Osteoarthritis Symptoms

Oct. 13, 2023 — Relief could be on the way for people with painful hand osteoarthritis after a new study found an affordable existing drug can help. Until now there has been no effective treatment. The paper ...

For Knee Replacement Patients, Physical Therapy Reduces Risk of Chronic Opioid Use

Oct. 27, 2021 — Even low levels of physical therapy were associated with lower risk of chronic opioid use after total knee replacement. The team's analysis of over 67,000 patient records revealed that the ...

Discovery Reveals Blocking Inflammation May Lead to Chronic Pain

May 12, 2022 — Using anti-inflammatory drugs and steroids to relieve pain could increase the chances of developing chronic pain. New research puts into question conventional practices used to alleviate pain. Normal ...

Researchers Suggest New Approach for Testing Treatments for Osteoarthritis

Oct. 12, 2023 — Osteoarthritis (OA) is the most common form of arthritis and is among the top 10 conditions contributing to Years Lived with Disability—a measure reflecting the impact an illness has on quality of ...

An Ice-Inspired Lubricant Improves Osteoarthritis Symptoms in Rats

Jan. 13, 2022 — With the Winter Olympics approaching, many people will soon be tuning in to watch events that take place on ice, such as figure skating, speed skating and ice hockey. An ultrathin, super-lubricating ...

Antidepressants Largely Ineffective for Back Pain and Osteoarthritis

Jan. 20, 2021 — Antidepressant drugs are largely ineffective for back and osteoarthritis pain, despite being widely used for these conditions, suggests a review of the ...

Molecule in the Nervous System May Hold Key to Treating Chronic Pain

June 13, 2022 — Researchers reveal a potential new way to treat chronic pain using anti-cancer drugs rather than opioid-based pain medication. Researchers identified the existence of a molecule in the nervous system ...

Nasal Cartilage Relieves Osteoarthritis in the Knee

Sep. 1, 2021 — Cartilage cells from the nasal septum can not only help repair cartilage injuries in the knee -- according to researchers, they can also withstand the chronic inflammatory tissue environment in ...

Quarter of Former Olympians Suffer from Osteoarthritis

Nov. 23, 2022 — Competing at elite level in sport is linked with an increased risk of developing osteoarthritis and joint pain in later life, a study suggests. One in four retired Olympians reported a diagnosis of ...

Osteoarthritis: New Genetic Risk Factors and Novel Drug Targets

Aug. 26, 2021 — Researchers have found new genetic risk factors for osteoarthritis and identified novel drug targets. Their finding is a milestone towards the development of the first ever curative treatment for ...

Health & Medicine News

December 6, 2023

Twin Research Indicates That a Vegan Diet Improves Cardiovascular Health

Nov. 30, 2023 — A recent trial of identical twins comparing vegan and omnivore diets found that a vegan diet improves overall cardiovascular ...

From the First Bite, Our Sense of Taste Helps Pace Our Eating

Nov. 22, 2023 — When you eagerly dig into a long-awaited dinner, signals from your stomach to your brain keep you from eating so much you'll regret it -- or so it's been ...

US Men Die 6 Years Before Women, as Life Expectancy Gap Widens

Nov. 14, 2023 — We've known for more than a century that women outlive men. But new research shows that, at least in the United States, the gap has been widening for more than a ...

Any Activity Is Better for Your Heart Than Sitting -- Even Sleeping

Nov. 9, 2023 — Replacing sitting with as little as a few minutes of moderate exercise a day tangibly improves heart health, according to new ...

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A Type of Allergy Medicine Might Help Treat Lung Cancer

Dec. 6, 2023 — Researchers have identified an allergy pathway that, when blocked, unleashes antitumor immunity in mouse models of non-small cell lung cancer (NSCLC). And in an early parallel study in humans, ...

New Research Shows How Important Protein Keeps Our Cell Membranes in Balance

Dec. 5, 2023 — New research shows how important protein keeps our cell membranes in balance. Researchers have studied the structure, function and mechanisms of the ...

Chaperoning Fat Storage: The Molecular Basis of Adiposity

Nov. 27, 2023 — Researchers found that HSP47, a collagen-specific chaperone, is a key determinant of body fat levels. HSP47 expression levels are upregulated with obesity and greater food intake and decreased with ...

Fungus-Fighting Protein Could Help Overcome Severe Autoimmune Disease and Cancer

Dec. 6, 2023 — A protein in the immune system programmed to protect the body from fungal infections is also responsible for exacerbating the severity of certain ...

Predicting Which of Our Organs Will Fail First

Dec. 6, 2023 — A new study demonstrates a simple way of studying organ aging by analyzing distinct proteins, or sets of them, in blood, enabling the prediction of individuals' risk for ...

Many Couples Around the World May Share High Blood Pressure

Dec. 6, 2023 — Spouses or partners in heterosexual relationships may have high blood pressure that mirrors one another, finds new, multinational ...

How Drugs Can Target the Thick 'Scar Tissue' of Pancreatic Cancer

Dec. 6, 2023 — Researchers discovered how anti-cancer drugs called HDAC inhibitors help treat pancreatic cancer by altering scar tissue (fibroblast) development. The findings suggest HDAC inhibitors could be ...

Repeated Blast Exposures May Harm the Brain Health of Military Personnel

Dec. 6, 2023 — The brains of special warfare community personnel repeatedly exposed to blasts show increased inflammation and structural changes compared with a control group, potentially increasing the risk of ...

New Findings Reveal Important Insights Into Age-Related Nonresolving Inflammation

Dec. 6, 2023 — Aging is associated with chronic, nonresolving inflammation, or 'inflammaging,' that can lead to tissue dysfunction. New findings reveal insights ...

Blood Hormone Levels Key to Identifying Which Post-Menopausal Women Will Benefit Most from Taking Anastrozole to Prevent Breast Cancer

Dec. 6, 2023 — has found that hormone levels, measured through blood tests, are an important indicator of whether women will benefit from recently licensed ...