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July 19, 2023 Researchers have developed a method to evaluate the folding stability of a million proteins simultaneously. DNA libraries were used to generate protein -- DNA complexes that were treated with enzymes ...
Oct. 19, 2023 Proteins are important molecules that perform a variety of functions essential to life. To function properly, many proteins must fold into specific structures. However, the way proteins fold into ...
Sep. 6, 2023 A team of researchers has revealed that the Dumpy protein, a component of extracellular matrices -- or ECM -- is the key factor in regulating the stereotypic origami-like folding of wing-cell sheets. ...
Mar. 23, 2022 In biophysics, the kinetic states of molecules play a determining role in the metabolic and physiological processes in which they take part. Now, a new article specifies for the first time the levels ...
May 17, 2022 Researchers have developed an advanced NMR (Nuclear Magnetic Resonance) method to monitor fast and complicated biomolecular events such as protein ...
July 14, 2022 Theoretical physicists put Google's artificial intelligence AlphaFold to the test and find the most complex protein knots so ...
Oct. 12, 2021 A team of researchers has announced a major new advance in understanding how our genetic information eventually translates into functional proteins -- one of the building blocks of human life. The ...
Dec. 5, 2022 New modeling shows how synonymous mutations -- those that change the DNA sequence of a gene but not the sequence of the encoded protein -- can still impact protein production and ...
July 12, 2022 Protein molecules require a defined shape in order to function. When they are created, their building blocks are therefore linked together in a very specific way. Researchers are now taking a closer ...
Sep. 14, 2023 Researchers have identified a backup mechanism of protein quality control which prevents the toxic effects of protein aggregation in specific tissues when normal methods of molecular monitoring fail. ...