Featured Research

from universities, journals, and other organizations

Genetically Engineered Animals Help In Scientific Research That May Benefit Children

Date:
September 22, 2005
Source:
Blackwell Publishing Ltd.
Summary:
The recent use of genetically modified mice and rats in combination with an animal model of obstructive nephropathy, a type of renal disease, has given researchers new insight in the development of kidney disease. This research is published in the September issue of Kidney International.

Sept. 21, 2005 - The recent use of genetically modified mice and ratsin combination with an animal model of obstructive nephropathy, a typeof renal disease, has given researchers new insight in the developmentof kidney disease. This research is published in the September issue ofKidney International.

Related Articles


"Chronic kidney disease is difficult to study since it takes a fairamount of time to install," states Joost P. Schanstra, Ph.D. of theInstituit Louis Bugnard inFrance. "This animal model has the advantageof mimicking in a short time the different stages of chronic kidneydisease. The combination of genetically engineered animals and thisanimal model has helped us to decide which molecules to study, or whichmight be interesting targets for drug development in human chronickidney disease."

Obstructive nephropathy or obstructive uropathy, the kidneydisease on which this animal model is based, is frequently found inchildren and is the first cause of end-stage renal disease (ESRD).According to the article, ESRD represents 16.1% of all pediatrictransplantations in North America.

###

This study is published in Kidney International.

Researchers Joost P. Schanstra and Jean-Loup Bascands currentlyhead the Renal Fibrosis Laboratory, which is part of the nationalinstitute of health and medical research (Inserm) in Toulouse, France.The RF-lab is fully able to design and carry out clinical researchfocused on newborn and childhood nephropathies and is currentlydeveloping research including prevention, mechanism and reversal oftubulointerstitial fibrosis.

About Kidney International
Kidney International, published on behalf of the International Societyof Nephrology, is one of the most cited journals in nephrology. KidneyInternational delivers current laboratory and clinical research onrenal medicine. This peer-reviewed, leading international journal isthe most authoritative forum for renal science and medicine. KidneyInternational continues to be a vital source of information forresearchers around the world. For additional information on thejournal, please visit www.blackwellpublishing.com/kid.

About the International Society of Nephrology
The International Society of Nephrology (ISN), a not-for-profitassociation founded in 1960, is committed to the worldwide advancementof education, science and patient care in nephrology. This goal isachieved by means of the Society's journals, the organization ofinternational congresses and symposia, and various outreach programsaround the world. The ISN acts as an international forum on nephrologyfor leading nephrologists as well as young investigators, from bothdeveloped and emerging countries. Further information is available at www.isn-online.org.

About Blackwell Publishing
Blackwell Publishing is the world's leading society publisher,partnering with more than 600 academic and professional societies.Blackwell publishes over 750 journals annually and, to date haspublished close to 6,000 text and reference books, across a wide rangeof academic, medical, and professional subjects.


Story Source:

The above story is based on materials provided by Blackwell Publishing Ltd.. Note: Materials may be edited for content and length.


Cite This Page:

Blackwell Publishing Ltd.. "Genetically Engineered Animals Help In Scientific Research That May Benefit Children." ScienceDaily. ScienceDaily, 22 September 2005. <www.sciencedaily.com/releases/2005/09/050922015144.htm>.
Blackwell Publishing Ltd.. (2005, September 22). Genetically Engineered Animals Help In Scientific Research That May Benefit Children. ScienceDaily. Retrieved December 18, 2014 from www.sciencedaily.com/releases/2005/09/050922015144.htm
Blackwell Publishing Ltd.. "Genetically Engineered Animals Help In Scientific Research That May Benefit Children." ScienceDaily. www.sciencedaily.com/releases/2005/09/050922015144.htm (accessed December 18, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, December 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Kids Die While Under Protective Services

Kids Die While Under Protective Services

AP (Dec. 18, 2014) As part of a six-month investigation of child maltreatment deaths, the AP found that hundreds of deaths from horrific abuse and neglect could have been prevented. AP's Haven Daley reports. (Dec. 18) Video provided by AP
Powered by NewsLook.com
UN: Up to One Million Facing Hunger in Ebola-Hit Countries

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

AFP (Dec. 17, 2014) Border closures, quarantines and crop losses in West African nations battling the Ebola virus could lead to as many as one million people going hungry, UN food agencies said on Wednesday. Duration: 00:52 Video provided by AFP
Powered by NewsLook.com
When You Lose Weight, This Is Where The Fat Goes

When You Lose Weight, This Is Where The Fat Goes

Newsy (Dec. 17, 2014) Can fat disappear into thin air? New research finds that during weight loss, over 80 percent of a person's fat molecules escape through the lungs. Video provided by Newsy
Powered by NewsLook.com
Why Your Boss Should Let You Sleep In

Why Your Boss Should Let You Sleep In

Newsy (Dec. 17, 2014) According to research out of the University of Pennsylvania, waking up for work is the biggest factor that causes Americans to lose sleep. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins