Featured Research

from universities, journals, and other organizations

Being An MRSA Carrier Increases Risk Of Infection And Death

Date:
July 3, 2008
Source:
Infectious Diseases Society of America
Summary:
Patients harboring methicillin-resistant Staphylococcus aureus for long periods of time continue to be at increased risk of MRSA infection and death, according to a new study.

Patients harboring methicillin-resistant Staphylococcus aureus (MRSA) for long periods of time continue to be at increased risk of MRSA infection and death, according to a new study in the July 15 issue of Clinical Infectious Diseases, currently available online.

MRSA is an antibiotic-resistant bacterium that can cause a variety of serious infections. The bacterium most commonly colonizes the nostrils, although it can be found in other body sites. Most research has focused on people who are newly colonized by the bacteria and has found that they are at substantial risk of subsequent infections. The new study shows that the increased risk of infection continues, with almost a quarter of MRSA-colonized patients developing infections after a year or more has passed since the colonization was confirmed. The infections include pneumonia and bloodstream events, and some infections were linked to deaths.

"Since infection risk remains substantial among long-term carriers of MRSA, these patients should be targeted for interventions to reduce subsequent risk of infection along with patients who newly acquire MRSA," said author Susan Huang, MD, MPH.

The researchers built on their previous work in this area, which showed that one-third of new MRSA carriers in a large tertiary care medical center developed infections within the year following the first detection of colonization. But, as, Dr. Huang points out, "risks beyond the first year of carriage were largely unknown."

In this study, Dr. Huang and coauthor Rupak Datta, MPH, followed 281 patients who had been MRSA-positive for at least one year and some for more than four years. Of these, 23 percent developed an MRSA infection within the year-long duration of this study. Pneumonia was the most common infection. MRSA was identified as a contributor to the deaths of 14 of the patients.

In their paper, the authors suggest that the MRSA infection risk may be more closely tied to a hospitalization event than to the duration of carriage: "We submit that these high risks of MRSA infection among culture-positive prevalent carriers are not only preferentially detected because of hospitalization, but may in fact be incurred because of device related, wound related, and immunologic declines associated with a current illness."

"One explanation for this may be that patients who have surgical wounds or intravenous lines may allow MRSA a route of entry and invasion that would not otherwise exist," added Dr. Huang.

The authors caution that because this study was performed in a large tertiary care medical center, they may have studied a disproportionate number of critically ill patients who could be at a relatively higher risk for infection. The results may not be generalizable to all patient settings.

Dr. Huang is currently an assistant professor in the Division of Infectious Diseases at the University of California Irvine. She was an infectious diseases physician at Brigham and Women's Hospital and an assistant professor at Harvard Medical School at the time this study was conducted.


Story Source:

The above story is based on materials provided by Infectious Diseases Society of America. Note: Materials may be edited for content and length.


Cite This Page:

Infectious Diseases Society of America. "Being An MRSA Carrier Increases Risk Of Infection And Death." ScienceDaily. ScienceDaily, 3 July 2008. <www.sciencedaily.com/releases/2008/07/080702103324.htm>.
Infectious Diseases Society of America. (2008, July 3). Being An MRSA Carrier Increases Risk Of Infection And Death. ScienceDaily. Retrieved August 27, 2014 from www.sciencedaily.com/releases/2008/07/080702103324.htm
Infectious Diseases Society of America. "Being An MRSA Carrier Increases Risk Of Infection And Death." ScienceDaily. www.sciencedaily.com/releases/2008/07/080702103324.htm (accessed August 27, 2014).

Share This




More Health & Medicine News

Wednesday, August 27, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Mini Pacemaker Has No Wires

Mini Pacemaker Has No Wires

Ivanhoe (Aug. 27, 2014) Cardiac experts are testing a new experimental device designed to eliminate major surgery and still keep the heart on track. Video provided by Ivanhoe
Powered by NewsLook.com
After Cancer: Rebuilding Breasts With Fat

After Cancer: Rebuilding Breasts With Fat

Ivanhoe (Aug. 27, 2014) More than 269 million women are diagnosed with breast cancer each year. Many of them will need surgery and radiation, but there’s a new simple way to reconstruct tissue using a patient’s own fat. Video provided by Ivanhoe
Powered by NewsLook.com
Blood Clots in Kids

Blood Clots in Kids

Ivanhoe (Aug. 27, 2014) Every year, up to 200,000 Americans die from a blood clot that travels to their lungs. You’ve heard about clots in adults, but new research shows kids can get them too. Video provided by Ivanhoe
Powered by NewsLook.com
Radio Waves Knock out Knee Pain

Radio Waves Knock out Knee Pain

Ivanhoe (Aug. 27, 2014) Doctors have used radio frequency ablation or RFA to reduce neck and back pain for years. But now, that same technique is providing longer-term relief for patients with severe knee pain. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins