Featured Research

from universities, journals, and other organizations

200,000 Rice Mutants Available Worldwide For Scientific Investigation

Date:
March 10, 2009
Source:
Virginia Tech
Summary:
Researchers have estimated the number of different rice mutants needed to have a mutant for every gene as somewhere between 180,698 and 460,000. Two hundred thousand rice mutants are now available and have been mapped.

Scientists across the world are building an extensive repository of genetically modified rice plants in the hope of understanding the function of the approximately 57,000 genes that make up the genome of Oryza sativa. The International Rice Functional Genomics Consortium recently announced the public availability of more than 200,000 rice mutant lines, which represent mutations in about half of the known functional genes mapped for rice to date. *

Related Articles


Researchers have estimated the number of different rice mutants needed to have a mutant for every gene as somewhere between 180,698 and 460,000. Two hundred thousand rice mutants are now available and have been mapped by the insertion of what are known as flanking sequence tags – small pieces of DNA or molecular tags that integrate into the rice genome. This approach is useful because it allows scientists to link a physical location on the genome to a specific gene and its visible feature or phenotype.

Arjun Krishnan, first author on the paper and a graduate student in Andy Pereira's laboratory at the Virginia Bioinformatics Institute, stated: "Bioinformatics is making it possible to visualize the vast amounts of sequence information available to researchers. The resources described in this paper, which are the combined output of many leading international rice research laboratories, mean that researchers can see and explore on their computers the precise positions of mutations in the rice genome sequence, for each rice mutant plant. About 50 percent of the protein-coding genes have knockout mutations, which probably abolish their expression and can provide valuable information on the genes by virtue of their loss of function. This is a significant milestone for the project and the availability of these rice plants represents a powerful resource for the rice genomics community."

More than 2 million rice mutants were generated in this project and the diversity of the available plants suits many of the experimental objectives of researchers looking at rice and other commercially important grasses. Mapping of the remaining genes from this population will be required to complete the resource. Many of them will be smaller genes less amenable to mutation that will pose significant challenges for researchers as they continue their work.

Dr. Andy Pereira, Professor at the Virginia Bioinformatics Institute, stated: "The Oryza sativa genome was sequenced in 2002 and researchers have come a long way since. Advances in technologies such as high-throughput sequencing and RNA interference gene silencing methods should help to accelerate the process of identifying the functions of the remaining genes in the rice genome." He added: "The availability of the rice mutant resource is already helping researchers in their quest to gain insights into the biology of this commercially important crop. These efforts are critical to understand gene function and, ultimately, the many biological processes that take place in rice and other grasses, including maize and wheat, which collectively produce our staple food."

* Krishnan A, Guiderdoni E, An G, Hsing YI, Han CD, Lee MC, Yu SM, Upadhyaya N, Ramachandran S, Zhang Q, Sundaresan V, Hirochika H, Leung H, Pereira A (2009) Plant Physiology 149(1): 165-170.


Story Source:

The above story is based on materials provided by Virginia Tech. Note: Materials may be edited for content and length.


Cite This Page:

Virginia Tech. "200,000 Rice Mutants Available Worldwide For Scientific Investigation." ScienceDaily. ScienceDaily, 10 March 2009. <www.sciencedaily.com/releases/2009/03/090304160402.htm>.
Virginia Tech. (2009, March 10). 200,000 Rice Mutants Available Worldwide For Scientific Investigation. ScienceDaily. Retrieved December 21, 2014 from www.sciencedaily.com/releases/2009/03/090304160402.htm
Virginia Tech. "200,000 Rice Mutants Available Worldwide For Scientific Investigation." ScienceDaily. www.sciencedaily.com/releases/2009/03/090304160402.htm (accessed December 21, 2014).

Share This


More From ScienceDaily



More Plants & Animals News

Sunday, December 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
Monarch Butterflies Descend Upon Mexican Forest During Annual Migration

Monarch Butterflies Descend Upon Mexican Forest During Annual Migration

Reuters - Light News Video Online (Dec. 19, 2014) Millions of monarch butterflies begin to descend onto Mexico as part of their annual migration south. Rough Cut (no reporter narration) Video provided by Reuters
Powered by NewsLook.com
The Best Protein-Filled Foods to Energize You for the New Year

The Best Protein-Filled Foods to Energize You for the New Year

Buzz60 (Dec. 19, 2014) The new year is coming and nothing will energize you more for 2015 than protein-filled foods. Fitness and nutrition expert John Basedow (@JohnBasedow) gives his favorite high protein foods that will help you build muscle, lose fat and have endless energy. Video provided by Buzz60
Powered by NewsLook.com
Birds Might Be Better Meteorologists Than Us

Birds Might Be Better Meteorologists Than Us

Newsy (Dec. 19, 2014) A new study suggests a certain type of bird was able to sense a tornado outbreak that moved through the U.S. a day before it hit. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins