Featured Research

from universities, journals, and other organizations

Odor coding in mammals is more complex than previously thought

Date:
October 26, 2010
Source:
Rockefeller University Press
Summary:
The contribution of odorant receptors to olfactory response in mammals is much more complex than previously thought, with important consequences for odorant encoding and information transfer about odorants to the brain.

A new study in the Journal of General Physiology (JGP) shows that the contribution of odorant receptors (ORs) to olfactory response in mammals is much more complex than previously thought, with important consequences for odorant encoding and information transfer about odorants to the brain.

Related Articles


ORs, which provide a system for mammals to discriminate between many different odors, form a large, diverse group of G protein-coupled receptors corresponding to around 1,000 functionally distinct receptors in rodents and 350 in humans. Besides providing odorant specificity to olfactory receptor neurons (ORNs) and contributing to ORN axon targeting, little is understood about the OR contribution to olfactory response.

Johannes Reisert, from the Monell Chemical Senses Center in Philadelphia, now demonstrates that different odorant receptors have varying degrees of basal activity, which drives receptor current fluctuations and basal action potential firing. This basal activity can be suppressed by odorants functioning as inverse agonists. Furthermore, odorant-stimulated olfactory receptor neurons expressing different odorant receptors can have strikingly different response patterns in the later phases of prolonged stimulation. Thus, basal activity differences, inhibitory antagonism, and late-phase response patterns may contribute heretofore unsuspected information used by the olfactory system in categorizing odorants.


Story Source:

The above story is based on materials provided by Rockefeller University Press. Note: Materials may be edited for content and length.


Journal Reference:

  1. J. Reisert. Origin of basal activity in mammalian olfactory receptor neurons. The Journal of General Physiology, 2010; 136 (5): 529 DOI: 10.1085/jgp.201010528

Cite This Page:

Rockefeller University Press. "Odor coding in mammals is more complex than previously thought." ScienceDaily. ScienceDaily, 26 October 2010. <www.sciencedaily.com/releases/2010/10/101025123850.htm>.
Rockefeller University Press. (2010, October 26). Odor coding in mammals is more complex than previously thought. ScienceDaily. Retrieved December 21, 2014 from www.sciencedaily.com/releases/2010/10/101025123850.htm
Rockefeller University Press. "Odor coding in mammals is more complex than previously thought." ScienceDaily. www.sciencedaily.com/releases/2010/10/101025123850.htm (accessed December 21, 2014).

Share This


More From ScienceDaily



More Plants & Animals News

Sunday, December 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
Monarch Butterflies Descend Upon Mexican Forest During Annual Migration

Monarch Butterflies Descend Upon Mexican Forest During Annual Migration

Reuters - Light News Video Online (Dec. 19, 2014) Millions of monarch butterflies begin to descend onto Mexico as part of their annual migration south. Rough Cut (no reporter narration) Video provided by Reuters
Powered by NewsLook.com
The Best Protein-Filled Foods to Energize You for the New Year

The Best Protein-Filled Foods to Energize You for the New Year

Buzz60 (Dec. 19, 2014) The new year is coming and nothing will energize you more for 2015 than protein-filled foods. Fitness and nutrition expert John Basedow (@JohnBasedow) gives his favorite high protein foods that will help you build muscle, lose fat and have endless energy. Video provided by Buzz60
Powered by NewsLook.com
Birds Might Be Better Meteorologists Than Us

Birds Might Be Better Meteorologists Than Us

Newsy (Dec. 19, 2014) A new study suggests a certain type of bird was able to sense a tornado outbreak that moved through the U.S. a day before it hit. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins