Featured Research

from universities, journals, and other organizations

New method for studying molecules discovered

Date:
November 18, 2010
Source:
Queen's University
Summary:
Researchers have discovered the method for studying oxygen in large molecular systems. The findings will help in the study of proteins, DNA, RNA and other molecular structures.

Queen's professor Gang Wu at the National Ultrahigh-Field NMR Facility for Solids in Ottawa.
Credit: Image courtesy of Queen's University

Researchers at Queen's University have discovered the method for studying oxygen in large molecular systems. The findings will help in the study of proteins, DNA, RNA and other molecular structures.

Related Articles


Biological molecules make up all living creatures on earth and contain four major elements -- hydrogen, carbon, nitrogen and oxygen. But until now scientists were only able to use nuclear magnetic resonance (NMR) to study three out of the four elements in the molecule puzzle because oxygen wavelengths were difficult to detect.

"Oxygen signals were so weak, so to speak, that no one could make use of them," says chemistry professor Gang Wu. "Now there is a way of detecting them even in complex biomolecular systems."

Dr. Wu and his colleagues used one of the strongest NMR spectrometers in the world, located at the National Ultrahigh-Field NMR Facility for Solids in Ottawa, to create a magnetic field in which oxygen's wavelength could be detected. They also enriched the oxygen in the molecule using isotope enrichment, and implemented new NMR techniques to boost the sensitivity for detecting weak signals.

The result is an amplified oxygen wavelength that can be studied. Scientists can now examine all four major elements and learn more about the chemical structure and interaction of large molecules.

Dr. Wu's colleagues include lead author and Queen's post-doctoral fellow Jianfeng Zhu, Eric Ye (University of Ottawa) and Victor Terskikh (NRC Steacie Institute for Molecular Sciences).

The findings were recently featured as a cover article in Angewandte Chemie.


Story Source:

The above story is based on materials provided by Queen's University. Note: Materials may be edited for content and length.


Journal Reference:

  1. Jianfeng Zhu, Eric Ye, Victor Terskikh, Gang Wu. Inside Cover: Solid-State 17O NMR Spectroscopy of Large Protein-Ligand Complexes (Angew. Chem. Int. Ed. 45/2010). Angewandte Chemie International Edition, 2010; 49 (45): 8278 DOI: 10.1002/anie.201004202

Cite This Page:

Queen's University. "New method for studying molecules discovered." ScienceDaily. ScienceDaily, 18 November 2010. <www.sciencedaily.com/releases/2010/11/101117184455.htm>.
Queen's University. (2010, November 18). New method for studying molecules discovered. ScienceDaily. Retrieved November 27, 2014 from www.sciencedaily.com/releases/2010/11/101117184455.htm
Queen's University. "New method for studying molecules discovered." ScienceDaily. www.sciencedaily.com/releases/2010/11/101117184455.htm (accessed November 27, 2014).

Share This


More From ScienceDaily



More Matter & Energy News

Thursday, November 27, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

NASA's First 3-D Printer In Space Creates Its First Object

NASA's First 3-D Printer In Space Creates Its First Object

Newsy (Nov. 26, 2014) The International Space Station is now using a proof-of-concept 3D printer to test additive printing in a weightless, isolated environment. Video provided by Newsy
Powered by NewsLook.com
Bolivian Recycling Initiative Turns Plastic Waste Into School Furniture

Bolivian Recycling Initiative Turns Plastic Waste Into School Furniture

Reuters - Innovations Video Online (Nov. 26, 2014) Innovative recycling project in La Paz separates city waste and converts plastic garbage into school furniture made from 'plastiwood'. Tara Cleary reports. Video provided by Reuters
Powered by NewsLook.com
Blu-Ray Discs Getting Second Run As Solar Panels

Blu-Ray Discs Getting Second Run As Solar Panels

Newsy (Nov. 26, 2014) Researchers at Northwestern University are repurposing Blu-ray movies for better solar panel technology thanks to the discs' internal structures. Video provided by Newsy
Powered by NewsLook.com
Today's Prostheses Are More Capable Than Ever

Today's Prostheses Are More Capable Than Ever

Newsy (Nov. 26, 2014) Advances in prosthetics are making replacement body parts stronger and more lifelike than they’ve ever been. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Space & Time

Matter & Energy

Computers & Math

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins