Featured Research

from universities, journals, and other organizations

New method for studying molecules discovered

Date:
November 18, 2010
Source:
Queen's University
Summary:
Researchers have discovered the method for studying oxygen in large molecular systems. The findings will help in the study of proteins, DNA, RNA and other molecular structures.

Queen's professor Gang Wu at the National Ultrahigh-Field NMR Facility for Solids in Ottawa.
Credit: Image courtesy of Queen's University

Researchers at Queen's University have discovered the method for studying oxygen in large molecular systems. The findings will help in the study of proteins, DNA, RNA and other molecular structures.

Biological molecules make up all living creatures on earth and contain four major elements -- hydrogen, carbon, nitrogen and oxygen. But until now scientists were only able to use nuclear magnetic resonance (NMR) to study three out of the four elements in the molecule puzzle because oxygen wavelengths were difficult to detect.

"Oxygen signals were so weak, so to speak, that no one could make use of them," says chemistry professor Gang Wu. "Now there is a way of detecting them even in complex biomolecular systems."

Dr. Wu and his colleagues used one of the strongest NMR spectrometers in the world, located at the National Ultrahigh-Field NMR Facility for Solids in Ottawa, to create a magnetic field in which oxygen's wavelength could be detected. They also enriched the oxygen in the molecule using isotope enrichment, and implemented new NMR techniques to boost the sensitivity for detecting weak signals.

The result is an amplified oxygen wavelength that can be studied. Scientists can now examine all four major elements and learn more about the chemical structure and interaction of large molecules.

Dr. Wu's colleagues include lead author and Queen's post-doctoral fellow Jianfeng Zhu, Eric Ye (University of Ottawa) and Victor Terskikh (NRC Steacie Institute for Molecular Sciences).

The findings were recently featured as a cover article in Angewandte Chemie.


Story Source:

The above story is based on materials provided by Queen's University. Note: Materials may be edited for content and length.


Journal Reference:

  1. Jianfeng Zhu, Eric Ye, Victor Terskikh, Gang Wu. Inside Cover: Solid-State 17O NMR Spectroscopy of Large Protein-Ligand Complexes (Angew. Chem. Int. Ed. 45/2010). Angewandte Chemie International Edition, 2010; 49 (45): 8278 DOI: 10.1002/anie.201004202

Cite This Page:

Queen's University. "New method for studying molecules discovered." ScienceDaily. ScienceDaily, 18 November 2010. <www.sciencedaily.com/releases/2010/11/101117184455.htm>.
Queen's University. (2010, November 18). New method for studying molecules discovered. ScienceDaily. Retrieved October 21, 2014 from www.sciencedaily.com/releases/2010/11/101117184455.htm
Queen's University. "New method for studying molecules discovered." ScienceDaily. www.sciencedaily.com/releases/2010/11/101117184455.htm (accessed October 21, 2014).

Share This



More Matter & Energy News

Tuesday, October 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Thanks, Marty McFly! Hoverboards Could Be Coming In 2015

Thanks, Marty McFly! Hoverboards Could Be Coming In 2015

Newsy (Oct. 21, 2014) If you've ever watched "Back to the Future Part II" and wanted to get your hands on a hoverboard, well, you might soon be in luck. Video provided by Newsy
Powered by NewsLook.com
Robots to Fly Planes Where Humans Can't

Robots to Fly Planes Where Humans Can't

Reuters - Innovations Video Online (Oct. 21, 2014) Researchers in South Korea are developing a robotic pilot that could potentially replace humans in the cockpit. Unlike drones and autopilot programs which are configured for specific aircraft, the robots' humanoid design will allow it to fly any type of plane with no additional sensors. Ben Gruber reports. Video provided by Reuters
Powered by NewsLook.com
Graphene Paint Offers Rust-Free Future

Graphene Paint Offers Rust-Free Future

Reuters - Innovations Video Online (Oct. 21, 2014) British scientists have developed a prototype graphene paint that can make coatings which are resistant to liquids, gases, and chemicals. The team says the paint could have a variety of uses, from stopping ships rusting to keeping food fresher for longer. Jim Drury reports. Video provided by Reuters
Powered by NewsLook.com
Massive Air Bag Recall Affects More Than 4.5 Million Vehicles

Massive Air Bag Recall Affects More Than 4.5 Million Vehicles

Reuters - US Online Video (Oct. 21, 2014) Major automakers are recalling millions of vehicles due to potentially defective front passenger air bag inflators that can rupture and spray metal shrapnel. Linda So reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Space & Time

Matter & Energy

Computers & Math

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins