Featured Research

from universities, journals, and other organizations

Yeast genomes: Genetic codes for species of yeasts identified and compared

Date:
June 22, 2011
Source:
Genetics Society of America
Summary:
A team of US researchers has identified and compared the genetic codes for all known species of yeasts closely related to bakers' and brewers' yeast (the former used in pizza dough, the latter in beer), which lays the foundation for future understanding of mutation and disease, as studies of yeasts often identify key genes and mechanisms of disease.

If you think yeast is most useful for beer and pizza crust, here's something else to chew on: a team of U.S. researchers has identified and compared the genetic codes for all known species of yeasts closely related to bakers' and brewers' yeast. This information, published in the Genetics Society of America's new open-access journal G3: Genes | Genomes | Genetics, lays the foundation for future understanding of mutation and disease, as studies of yeasts often identify key genes and mechanisms of disease.

Related Articles


"We hope to learn to read the language of DNA and tell when mutations or differences will cause disease and when they will be advantageous," said Chris Todd Hittinger, senior author of the work from the Department of Biochemistry and Molecular Genetics at the University of Colorado School of Medicine in Aurora, Colorado. "Providing a complete catalog of diversity among this group of species will allow us to quickly test which changes are responsible for which functions in the laboratory with a level of precision and efficiency not possible in other organisms."

Using massively parallel next-generation DNA sequencing, the researchers determined the genome sequences, doubling the number of genes available for comparison, and identifying which genes changed in which species. They did this by segmenting each organism's DNA into small pieces, and then computationally "reassembled" the pieces and compared them to the genome of S. cerevisiae (the species used to make beer, bread, wine, etc.) to identify similarities and differences. The researchers also genetically engineered several of the strains to make them amenable for experimentation. Results from this study will allow researchers to compare the genetics, molecular biology, and ecology of these species. Because yeast genomes and lifestyles are relatively simple, determining how diversity is encoded in their DNA is much easier than with more complex organisms, such as humans.

"The experimental resources described in this paper extend the value of yeasts for understanding biological processes," said Brenda Andrews, Editor-in-Chief of G3: Genes | Genomes | Genetics, "and if they help us make better pizza crust and beer along the way, all the better."


Story Source:

The above story is based on materials provided by Genetics Society of America. Note: Materials may be edited for content and length.


Journal Reference:

  1. Devin R. Scannell, Oliver A. Zill, Antonis Rokas, Celia Payen, Maitreya J. Dunham, Michael B. Eisen, Jasper Rine, Mark Johnston, Chris Todd Hittinger. The Awesome Power of Yeast Evolutionary Genetics: New Genome Sequences and Strain Resources for the Saccharomyces sensu stricto Genus. G3: Genes | Genomes | Genetics, 2011; 1 (1): 11-25 DOI: 10.1534/g3.111.000273

Cite This Page:

Genetics Society of America. "Yeast genomes: Genetic codes for species of yeasts identified and compared." ScienceDaily. ScienceDaily, 22 June 2011. <www.sciencedaily.com/releases/2011/06/110621164725.htm>.
Genetics Society of America. (2011, June 22). Yeast genomes: Genetic codes for species of yeasts identified and compared. ScienceDaily. Retrieved March 2, 2015 from www.sciencedaily.com/releases/2011/06/110621164725.htm
Genetics Society of America. "Yeast genomes: Genetic codes for species of yeasts identified and compared." ScienceDaily. www.sciencedaily.com/releases/2011/06/110621164725.htm (accessed March 2, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, March 2, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

GlaxoSmithKline and Novartis Try Swapping Success

GlaxoSmithKline and Novartis Try Swapping Success

Reuters - Business Video Online (Mar. 2, 2015) GlaxoSmithKline and Novartis have completed a series of asset swaps worth more than $20 billion. As Grace Pascoe reports they say the deal will reshape both drugmakers. Video provided by Reuters
Powered by NewsLook.com
How Can West Africa Rebuild After Ebola?

How Can West Africa Rebuild After Ebola?

Reuters - Business Video Online (Mar. 2, 2015) How best to rebuild the three West African countries struggling with Ebola will be discussed in Brussels this week. As Hayley Platt reports Sierra Leone has the toughest job ahead - its once thriving economy has been ravaged by the disease. Video provided by Reuters
Powered by NewsLook.com
Doctors Often Give In To Vaccine-Wary Parents

Doctors Often Give In To Vaccine-Wary Parents

Newsy (Mar. 2, 2015) A new survey published in the journal Pediatrics found many doctors are giving in to parents&apos; requests to delay vaccinating their children. Video provided by Newsy
Powered by NewsLook.com
The Best Ways To Celebrate National Nutrition Month

The Best Ways To Celebrate National Nutrition Month

Buzz60 (Mar. 2, 2015) Just when your New Year&apos;s Resolution is losing steam, March comes with fresh inspiration. TC Newman (@PurpleTCNewman) has some tips to incorporate into your lifestyle during National Nutrition Month. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins