Featured Research

from universities, journals, and other organizations

Live-action films of worm sperm help researchers track critical fertility enzymes

Date:
November 14, 2011
Source:
San Francisco State University
Summary:
Compared to most other cells in an organism, sperm undergo a radical transformation to become compact and mobile delivery systems for paternal DNA. Even though sperm looks and moves quite differently across species, researchers now say that there are at least a few key enzymes that are critical for sperm development and mobility in species as different as mice and nematode worms.

Compared to most other cells in an organism, sperm undergo a radical transformation to become compact and mobile delivery systems for paternal DNA. Even though sperm looks and moves quite differently across species, SF State researcher Diana Chu and colleagues now say that there are at least a few key enzymes that are critical for sperm development and mobility in species as different as mice and nematode worms.

Related Articles


The study by Chu, et al., was published online in the journal Genetics.

These enzymes (called PP1 phosphatases) are multitaskers in the nematode, which Chu and the others discovered through unique live-action films of the enzymes at work. First, the enzymes help to separate chromosomes during sperm cell division. After that, they play a role in the development of the sperm's pseudopods -- the appendages that nematode sperm use to move. Pseudopods propel the sperm with a "treadmilling" motion, and the enzymes help disassemble the cell's inner skeleton in a way that pushes the treadmilling forward.

Sperm in mammals like mice -- and men -- don't have pseudopods and don't move in the same way, but they still rely on the phosphatases for development and mobility. Further study of the phosphatases could someday shed light on some of the causes of human infertility, since the enzymes seem to be critical for sperm function.


Story Source:

The above story is based on materials provided by San Francisco State University. Note: Materials may be edited for content and length.


Journal Reference:

  1. J.-c. Wu, A. C. Go, M. Samson, T. Cintra, S. Mirsoian, T. F. Wu, M. M. Jow, E. J. Routman, D. S. Chu. PP1 Phosphatases Regulate Multiple Stages of Sperm Development and Motility in Caenorhabditis elegans. Genetics, 2011; DOI: 10.1534/genetics.111.135376

Cite This Page:

San Francisco State University. "Live-action films of worm sperm help researchers track critical fertility enzymes." ScienceDaily. ScienceDaily, 14 November 2011. <www.sciencedaily.com/releases/2011/11/111101125559.htm>.
San Francisco State University. (2011, November 14). Live-action films of worm sperm help researchers track critical fertility enzymes. ScienceDaily. Retrieved December 21, 2014 from www.sciencedaily.com/releases/2011/11/111101125559.htm
San Francisco State University. "Live-action films of worm sperm help researchers track critical fertility enzymes." ScienceDaily. www.sciencedaily.com/releases/2011/11/111101125559.htm (accessed December 21, 2014).

Share This


More From ScienceDaily



More Plants & Animals News

Sunday, December 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
Monarch Butterflies Descend Upon Mexican Forest During Annual Migration

Monarch Butterflies Descend Upon Mexican Forest During Annual Migration

Reuters - Light News Video Online (Dec. 19, 2014) Millions of monarch butterflies begin to descend onto Mexico as part of their annual migration south. Rough Cut (no reporter narration) Video provided by Reuters
Powered by NewsLook.com
The Best Protein-Filled Foods to Energize You for the New Year

The Best Protein-Filled Foods to Energize You for the New Year

Buzz60 (Dec. 19, 2014) The new year is coming and nothing will energize you more for 2015 than protein-filled foods. Fitness and nutrition expert John Basedow (@JohnBasedow) gives his favorite high protein foods that will help you build muscle, lose fat and have endless energy. Video provided by Buzz60
Powered by NewsLook.com
Birds Might Be Better Meteorologists Than Us

Birds Might Be Better Meteorologists Than Us

Newsy (Dec. 19, 2014) A new study suggests a certain type of bird was able to sense a tornado outbreak that moved through the U.S. a day before it hit. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins