Featured Research

from universities, journals, and other organizations

Live-action films of worm sperm help researchers track critical fertility enzymes

Date:
November 14, 2011
Source:
San Francisco State University
Summary:
Compared to most other cells in an organism, sperm undergo a radical transformation to become compact and mobile delivery systems for paternal DNA. Even though sperm looks and moves quite differently across species, researchers now say that there are at least a few key enzymes that are critical for sperm development and mobility in species as different as mice and nematode worms.

Compared to most other cells in an organism, sperm undergo a radical transformation to become compact and mobile delivery systems for paternal DNA. Even though sperm looks and moves quite differently across species, SF State researcher Diana Chu and colleagues now say that there are at least a few key enzymes that are critical for sperm development and mobility in species as different as mice and nematode worms.

Related Articles


The study by Chu, et al., was published online in the journal Genetics.

These enzymes (called PP1 phosphatases) are multitaskers in the nematode, which Chu and the others discovered through unique live-action films of the enzymes at work. First, the enzymes help to separate chromosomes during sperm cell division. After that, they play a role in the development of the sperm's pseudopods -- the appendages that nematode sperm use to move. Pseudopods propel the sperm with a "treadmilling" motion, and the enzymes help disassemble the cell's inner skeleton in a way that pushes the treadmilling forward.

Sperm in mammals like mice -- and men -- don't have pseudopods and don't move in the same way, but they still rely on the phosphatases for development and mobility. Further study of the phosphatases could someday shed light on some of the causes of human infertility, since the enzymes seem to be critical for sperm function.


Story Source:

The above story is based on materials provided by San Francisco State University. Note: Materials may be edited for content and length.


Journal Reference:

  1. J.-c. Wu, A. C. Go, M. Samson, T. Cintra, S. Mirsoian, T. F. Wu, M. M. Jow, E. J. Routman, D. S. Chu. PP1 Phosphatases Regulate Multiple Stages of Sperm Development and Motility in Caenorhabditis elegans. Genetics, 2011; DOI: 10.1534/genetics.111.135376

Cite This Page:

San Francisco State University. "Live-action films of worm sperm help researchers track critical fertility enzymes." ScienceDaily. ScienceDaily, 14 November 2011. <www.sciencedaily.com/releases/2011/11/111101125559.htm>.
San Francisco State University. (2011, November 14). Live-action films of worm sperm help researchers track critical fertility enzymes. ScienceDaily. Retrieved February 27, 2015 from www.sciencedaily.com/releases/2011/11/111101125559.htm
San Francisco State University. "Live-action films of worm sperm help researchers track critical fertility enzymes." ScienceDaily. www.sciencedaily.com/releases/2011/11/111101125559.htm (accessed February 27, 2015).

Share This


More From ScienceDaily



More Plants & Animals News

Friday, February 27, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Amazon Keeps Its Green Thanks To The Sahara Desert

The Amazon Keeps Its Green Thanks To The Sahara Desert

Newsy (Feb. 25, 2015) Satellite data shows the Amazon rainforest supports its lush flora with a little help from Sahara Desert dust. Video provided by Newsy
Powered by NewsLook.com
Mayor Says District of Columbia to Go Ahead With Pot Legalization

Mayor Says District of Columbia to Go Ahead With Pot Legalization

Reuters - News Video Online (Feb. 25, 2015) Washington&apos;s mayor says the District of Columbia will move forward with marijuana legalization, despite pushback from Congress. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
Marijuana Nowhere Near As Deadly As Alcohol: Study

Marijuana Nowhere Near As Deadly As Alcohol: Study

Newsy (Feb. 25, 2015) A new study says marijuana is about 114 times less deadly than alcohol. Video provided by Newsy
Powered by NewsLook.com
Fox With Horrifying Injury Rescued and Released Back Into the Wild

Fox With Horrifying Injury Rescued and Released Back Into the Wild

RightThisMinute (Feb. 25, 2015) This wounded fox knew what she was doing when she wandered into the yard of a nature photographer. The photographer got "Scamp" immediately in the hands of Wildlife Aid and she was released back into the wild in no time. Video provided by RightThisMinute
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins