Science News
from research organizations

What causes the excess rate of death associated with alcohol use disorders?

Date:
April 20, 2016
Source:
The JAMA Network Journals
Summary:
To what degree does the excess rate of death in individuals with alcohol use disorder (AUD) happen because of a predisposition in the person who develops AUD compared with the direct effect of the AUD itself?
Share:
FULL STORY

To what degree does the excess rate of death in individuals with alcohol use disorder (AUD) happen because of a predisposition in the person who develops AUD compared with the direct effect of the AUD itself?

That's the question Kenneth S. Kendler, M.D., of Virginia Commonwealth University, Richmond, and coauthors examined using Swedish registry information for members of the general population and half-siblings, full-siblings and monozygotic twins discordant (differing) on AUD, according to a new article published online by JAMA Psychiatry.

The authors report AUD was associated with excess mortality. The excess death associated with AUD appears to come from both the predisposition of the person who develops AUD and as a direct result of having AUD. The effect of predisposition to AUD was more prominent when people were younger and in the earlier years of AUD and the direct effect of AUD became more important later in life and later in the course of AUD.

"These results have clear implications for interventions that seek to reduce the substantially elevated rates of mortality in those with AUD," the authors conclude.


Story Source:

Materials provided by The JAMA Network Journals. Note: Content may be edited for style and length.


Journal Reference:

  1. Kenneth S. Kendler, Henrik Ohlsson, Jan Sundquist, Kristina Sundquist. Alcohol Use Disorder and Mortality Across the Lifespan. JAMA Psychiatry, 2016; DOI: 10.1001/jamapsychiatry.2016.0360

Cite This Page:

The JAMA Network Journals. "What causes the excess rate of death associated with alcohol use disorders?." ScienceDaily. ScienceDaily, 20 April 2016. <www.sciencedaily.com/releases/2016/04/160420120324.htm>.
The JAMA Network Journals. (2016, April 20). What causes the excess rate of death associated with alcohol use disorders?. ScienceDaily. Retrieved May 23, 2017 from www.sciencedaily.com/releases/2016/04/160420120324.htm
The JAMA Network Journals. "What causes the excess rate of death associated with alcohol use disorders?." ScienceDaily. www.sciencedaily.com/releases/2016/04/160420120324.htm (accessed May 23, 2017).

RELATED STORIES