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Piezoelectric effect of lysozyme was experimentally proved

Substance generates an electric charge, can replace the batteries in the pacemakers, say researchers

Date:
November 27, 2017
Source:
Ural Federal University
Summary:
Direct evidence of the piezoelectric effect of lysozyme in monoclinic and tetragonal aggregate films of lysozyme has now been captured by researchers. The sufficiently high piezoelectric coefficient is several times higher than that of the classical quartz piezoelectricity, which makes it possible to use this material for various biomedical purposes, for example, to generate electric charges in cells.
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A group of researchers from the University of Limerick (Ireland) and Ural Federal University (Russia) received direct evidence of the piezoelectric effect of lysozyme in monoclinic and tetragonal aggregate films of lysozyme. The sufficiently high piezoelectric coefficient is several times higher than that of the classical quartz piezoelectricity, which makes it possible to use this material for various biomedical purposes, for example, to generate electric charges in cells. This means that lysozyme can be used to stimulate nerve endings by generating electrical signals directly in the body; it can serve as a power source for pacemakers (instead of regular batteries that must be periodically replaced). Moreover lysozyme can be used in various biosensors to detect specific markers of diseases.

"Lysozyme plays a big role in the physiological processes in the human body, and its concentration serves as a marker for various diseases. Lysozyme easily crystallizes, its structure was obtained back in 1965. It was assumed that lysozyme single crystals can have a piezoelectric effect, which means they can generate electric charge at mechanical pressure and deform under the action of an electric field," explains co-author of the study, head of the Laboratory of Nanoscale Ferroelectric Materials of UrFU Andrei Kholkin.

However, the scientists have obtained direct evidence of piezoelectric activity of lysozyme and confirmed the existence of a connection between the functionality of living organisms and the physical properties of its constituent structures only recently. The results of the study are presented in the article "The direct piezoelectric effect in the globular protein lysozyme" in the journal American Institute of Physics.


Story Source:

Materials provided by Ural Federal University. Note: Content may be edited for style and length.


Journal Reference:

  1. A. Stapleton, M. R. Noor, J. Sweeney, V. Casey, A. L. Kholkin, C. Silien, A. A. Gandhi, T. Soulimane, S. A. M. Tofail. The direct piezoelectric effect in the globular protein lysozyme. Applied Physics Letters, 2017; 111 (14): 142902 DOI: 10.1063/1.4997446

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Ural Federal University. "Piezoelectric effect of lysozyme was experimentally proved." ScienceDaily. ScienceDaily, 27 November 2017. <www.sciencedaily.com/releases/2017/11/171127094954.htm>.
Ural Federal University. (2017, November 27). Piezoelectric effect of lysozyme was experimentally proved. ScienceDaily. Retrieved May 25, 2024 from www.sciencedaily.com/releases/2017/11/171127094954.htm
Ural Federal University. "Piezoelectric effect of lysozyme was experimentally proved." ScienceDaily. www.sciencedaily.com/releases/2017/11/171127094954.htm (accessed May 25, 2024).

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