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Intestinal worms may solve allergy puzzle

Date:
December 4, 2017
Source:
University of Bergen
Summary:
While young people with parasite worms currently have a four times higher risk for developing allergies and asthma than others, their parents are generally unaffected. Researchers were surprised when they found that intestinal worms, so-called Helminths (Toxocara Canis) from animals, actually have an influence on allergy- and asthma risk in humans.
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While young people with parasite worms currently have a four times higher risk for developing allergies and asthma than others. Their parents are generally unaffected.

Researchers at the University of Bergen (UiB) in Norway were surprised when they found that intestinal worms, so-called Helminths (Toxocara Canis) from animals, actually have an influence on allergy- and asthma risk in humans.

Their results showed that young people who test positive for this parasite, have a 4 times higher risk of developing asthma and allergies than others.

"Usually, we consider a 50% higher risk as being high, but here we see a 400% higher risk," says Professor Cecilie Svanes at Centre for International Health, UiB.

Key to allergy puzzle

According to Svanes, what is interesting in these results is that it seems to be only the young generation who has higher risk of getting asthma and allergies if they test positive on helminths, and not their parents.

"We do not know why the parasite only influences the young generation in a negative way and not their parents. If we can discover the reason for this, I think we will have solved the puzzle of why allergies have increased enormously over the past few decades," says Svanes.

Allergy explosion

Many studies show that the numbers of people with asthma and allergies have increased enormously over the past few decades. The reason for this is unknown.

"One of the most common hypotheses is that we have become more in contact with chemicals and less in contact with microbes and bacteria," Svanes explains.

"There are, however, many things that have changed during the last decades. Nobody knows why allergy and asthma levels have increased. The phenomena is happening all over the world. It probably relates to urbanisation among other things."


Story Source:

Materials provided by University of Bergen. Note: Content may be edited for style and length.


Journal Reference:

  1. Nils Oskar Jõgi, Cecilie Svanes, Silver Peeter Siiak, Erin Logan, John W. Holloway, Jannicke Igland, Ane Johannessen, Michael Levin, Francisco Gomez Real, Vivi Schlunssen, William G C Horsnell, Randi J. Bertelsen. Zoonotic helminth exposure and risk of allergic diseases: a study of two generations in Norway. Clinical & Experimental Allergy, 2017; DOI: 10.1111/cea.13055

Cite This Page:

University of Bergen. "Intestinal worms may solve allergy puzzle." ScienceDaily. ScienceDaily, 4 December 2017. <www.sciencedaily.com/releases/2017/12/171204091811.htm>.
University of Bergen. (2017, December 4). Intestinal worms may solve allergy puzzle. ScienceDaily. Retrieved October 9, 2024 from www.sciencedaily.com/releases/2017/12/171204091811.htm
University of Bergen. "Intestinal worms may solve allergy puzzle." ScienceDaily. www.sciencedaily.com/releases/2017/12/171204091811.htm (accessed October 9, 2024).

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