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Risk of non-infectious elephantiasis mapped in Cameroon

Date:
January 11, 2018
Source:
PLOS
Summary:
Both the etiology and demographics of podoconiosis, a non-infectious disease which causes massive swelling of the legs, are poorly understood. To help contribute to the global atlas of podoconiosis knowledge, researchers have now described the distribution of podoconiosis in Cameroon.
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Both the etiology and demographics of podoconiosis, a non-infectious disease which causes massive swelling of the legs, are poorly understood. To help contribute to the global atlas of podoconiosis knowledge, researchers reporting in PLOS Neglected Tropical Diseases have now described the distribution of podoconiosis in Cameroon.

Podoconiosis, a non-filarial form of elephantiasis which was identified as a neglected tropical disease by the World Health Organization in 2011, arises in barefoot subsistence farmers who are in frequent contact with red volcanic clay soil. Podoconiosis is one of several neglected diseases causing pain, disability and disfigurement that contribute to the world's poorest and most vulnerable communities remaining in a cycle of poverty and disease. The disease has been reported in more than 32 countries, with an estimated 4 million cases worldwide. However, Ethiopia is the only country where podoconiosis risk has been extensively mapped.

Specific control methods include the use of footwear, regular foot hygiene and floor coverings. For those with the diseases management of the lymphedema-related morbidity is recommended which includes foot hygiene, foot care, wound care, compression, exercises, elevation of the legs and treatment of acute infections.

In the new work, Kebebe Deribe, Postdoctoral Research Fellow of Brighton and Sussex Medical School, UK, and colleagues, sampled 76 villages from 40 health districts in Cameroon. In each village, all individuals age 15 and older were surveyed and screened for lymphedema -- the swelling that is indicative of elephantiasis. In cases of lymphedema, other diagnoses, including the filarial forms of elephantiasis, were excluded using field tests.

Overall, 10,178 individuals from 4,603 households participated. 83 people with lymphedema were identified and 52 diagnosed with podoconiosis. The overall prevalence of podoconiosis was found to be 0.5%, and at least one case was found in every region, suggesting a low prevalence but nationwide distribution of the disease in Cameroon.

Dr. Deribe concludes: "We have clear prevention and control strategies, and can beat this disabling disease in one generation. We must do more to improve podoconiosis control in high-risk countries by increasing coverage with proven interventions, such as footwear and foot washing. The elimination of podoconiosis requires a combination of political will, policy formulation and operational and financial commitment by governments of endemic countries and donors."


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Journal Reference:

  1. Kebede Deribe, Amuam Andrew Beng, Jorge Cano, Abdel Jelil Njouendo, Jerome Fru-Cho, Abong Raphael Awah, Mathias Esum Eyong, Patrick W. Chounna Ndongmo, Emanuele Giorgi, David M. Pigott, Nick Golding, Rachel L. Pullan, Abdisalan M. Noor, Fikre Enquselassie, Christopher J. L. Murray, Simon J. Brooker, Simon I. Hay, Peter Enyong, Melanie J. Newport, Samuel Wanji, Gail Davey. Mapping the geographical distribution of podoconiosis in Cameroon using parasitological, serological, and clinical evidence to exclude other causes of lymphedema. PLOS Neglected Tropical Diseases, 2018; 12 (1): e0006126 DOI: 10.1371/journal.pntd.0006126

Cite This Page:

PLOS. "Risk of non-infectious elephantiasis mapped in Cameroon." ScienceDaily. ScienceDaily, 11 January 2018. <www.sciencedaily.com/releases/2018/01/180111141746.htm>.
PLOS. (2018, January 11). Risk of non-infectious elephantiasis mapped in Cameroon. ScienceDaily. Retrieved March 28, 2024 from www.sciencedaily.com/releases/2018/01/180111141746.htm
PLOS. "Risk of non-infectious elephantiasis mapped in Cameroon." ScienceDaily. www.sciencedaily.com/releases/2018/01/180111141746.htm (accessed March 28, 2024).

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