New! Sign up for our free email newsletter.
Science News
from research organizations

Artificial sweeteners have toxic effects on gut microbes

Date:
October 1, 2018
Source:
American Associates, Ben-Gurion University of the Negev
Summary:
The collaborative study indicated relative toxicity of six artificial sweeteners (aspartame, sucralose, saccharine, neotame, advantame, and acesulfame potassium-k) and 10 sport supplements containing these artificial sweeteners. The bacteria found in the digestive system became toxic when exposed to concentrations of only one mg./ml. of the artificial sweeteners.
Share:
FULL STORY

FDA-approved artificial sweeteners and sport supplements were found to be toxic to digestive gut microbes, according to a new paper published in Molecules by researchers at Ben-Gurion University of the Negev (BGU) in Israel and Nanyang Technological University in Singapore.

The collaborative study indicated relative toxicity of six artificial sweeteners (aspartame, sucralose, saccharine, neotame, advantame, and acesulfame potassium-k) and 10 sport supplements containing these artificial sweeteners. The bacteria found in the digestive system became toxic when exposed to concentrations of only one mg./ml. of the artificial sweeteners.

"We modified bioluminescent E. coli bacteria, which luminesce when they detect toxicants and act as a sensing model representative of the complex microbial system," says Prof. Ariel Kushmaro, John A. Ungar Chair in Biotechnology in the Avram and Stella Goldstein-Goren Department of Biotechnology Engineering, and member of the Ilse Katz Institute for Nanoscale Science and Technology and the National Institute for Biotechnology in the Negev. "This is further evidence that consumption of artificial sweeteners adversely affects gut microbial activity which can cause a wide range of health issues."

Artificial sweeteners are used in countless food products and soft drinks with reduced sugar content. Many people consume this added ingredient without their knowledge. Moreover, artificial sweeteners have been identified as emerging environmental pollutants, and can be found in drinking and surface water, and groundwater aquifers.

"The results of this study might help in understanding the relative toxicity of artificial sweeteners and the potential of negative effects on the gut microbial community as well as the environment.

Furthermore, the tested bioluminescent bacterial panel can potentially be used for detecting artificial sweeteners in the environment," says Prof. Kushmaro.


Story Source:

Materials provided by American Associates, Ben-Gurion University of the Negev. Note: Content may be edited for style and length.


Journal Reference:

  1. Dorin Harpaz, Loo Yeo, Francesca Cecchini, Trish Koon, Ariel Kushmaro, Alfred Tok, Robert Marks, Evgeni Eltzov. Measuring Artificial Sweeteners Toxicity Using a Bioluminescent Bacterial Panel. Molecules, 2018; 23 (10): 2454 DOI: 10.3390/molecules23102454

Cite This Page:

American Associates, Ben-Gurion University of the Negev. "Artificial sweeteners have toxic effects on gut microbes." ScienceDaily. ScienceDaily, 1 October 2018. <www.sciencedaily.com/releases/2018/10/181001101932.htm>.
American Associates, Ben-Gurion University of the Negev. (2018, October 1). Artificial sweeteners have toxic effects on gut microbes. ScienceDaily. Retrieved April 12, 2024 from www.sciencedaily.com/releases/2018/10/181001101932.htm
American Associates, Ben-Gurion University of the Negev. "Artificial sweeteners have toxic effects on gut microbes." ScienceDaily. www.sciencedaily.com/releases/2018/10/181001101932.htm (accessed April 12, 2024).

Explore More

from ScienceDaily

RELATED STORIES