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Chest CT findings in coronavirus disease (COVID-19) pneumonia

Date:
March 3, 2020
Source:
American Roentgen Ray Society
Summary:
New research on the novel coronavirus (COVID-19) is a multi-center study (n=101) of the relationship between chest CT findings and the clinical conditions of COVID-19 pneumonia -- which determined that most patients with the disease have ground-glass opacities (GGO) (86.1%) or mixed GGO and consolidation (64.4%) and vascular enlargement in the lesion (71.3%). CT involvement score can help evaluate the severity and extent of COVID-19 pneumonia.
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A multi-center study (n=101) of the relationship between chest CT findings and the clinical conditions of coronavirus disease (COVID-19) pneumonia -- published ahead-of-print and open-access in the American Journal of Roentgenology (AJR) -- determined that most patients with COVID-19 pneumonia have ground-glass opacities (GGO) (86.1%) or mixed GGO and consolidation (64.4%) and vascular enlargement in the lesion (71.3%).

In addition, lead authors Wei Zhao, Zheng Zhong, and colleagues revealed that lesions present on CT images were more likely to have peripheral distribution (87.1%) and bilateral involvement (82.2%) and be lower lung predominant (54.5%) and multifocal (54.5%).

Zhao, Zhong, et al. collected their 101 cases of COVID-19 pneumonia across four institutions in China's Hunan province, comparing clinical characteristics and imaging features between two groups: nonemergency (mild or common disease) and emergency (severe or fatal disease).

Accordingly, most of the cohort (70.2%) were 21-50 years old, and most patients (78.2%) had fever as the onset symptom. Only five patients showed disease associated with a family outbreak.

While the emergency group patients were older than the patients in the nonemergency group, the rate of underlying disease was not significantly different in the two groups -- suggesting that viral load could be a better reflection of the severity and extent of COVID-19 pneumonia.

As Zhao and Zhong explained further: "Architectural distortion, traction bronchiectasis, and pleural effusions, which may reflect the viral load and virulence of COVID-19, were statistically different between the two groups and may help us to identify the emergency type disease."

The authors of this AJR article also noted that CT involvement score can help evaluate the severity and extent of COVID-19 pneumonia.


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Materials provided by American Roentgen Ray Society. Note: Content may be edited for style and length.


Journal Reference:

  1. Wei Zhao, Zheng Zhong, Xingzhi Xie, Qizhi Yu, Jun Liu. Relation Between Chest CT Findings and Clinical Conditions of Coronavirus Disease (COVID-19) Pneumonia: A Multicenter Study. American Journal of Roentgenology, 2020; 1 DOI: 10.2214/AJR.20.22976

Cite This Page:

American Roentgen Ray Society. "Chest CT findings in coronavirus disease (COVID-19) pneumonia." ScienceDaily. ScienceDaily, 3 March 2020. <www.sciencedaily.com/releases/2020/03/200303175318.htm>.
American Roentgen Ray Society. (2020, March 3). Chest CT findings in coronavirus disease (COVID-19) pneumonia. ScienceDaily. Retrieved April 14, 2024 from www.sciencedaily.com/releases/2020/03/200303175318.htm
American Roentgen Ray Society. "Chest CT findings in coronavirus disease (COVID-19) pneumonia." ScienceDaily. www.sciencedaily.com/releases/2020/03/200303175318.htm (accessed April 14, 2024).

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