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Study Shows Why Some Immune Systems Control HIV

Date:
October 8, 2002
Source:
NIH/National Institute Of Allergy And Infectious Diseases
Summary:
Scientists are beginning to change their thinking about why the immune systems of most people infected with HIV cannot control the spread of the virus while the immune systems of a rare group of individuals, called long-term nonprogressors, can. For some time, scientists thought that people who could not control HIV had too few HIV-fighting white blood cells called CD8+ T cells. However, a new study suggests the difference is not the number but the quality of these cells: both nonprogressors and others have about the same number of HIV-fighting CD8+ T cells, but the cells of nonprogressors function better.

Scientists are beginning to change their thinking about why the immune systems of most people infected with HIV cannot control the spread of the virus while the immune systems of a rare group of individuals, called long-term nonprogressors, can. For some time, scientists thought that people who could not control HIV had too few HIV-fighting white blood cells called CD8+ T cells. However, a new study suggests the difference is not the number but the quality of these cells: both nonprogressors and others have about the same number of HIV-fighting CD8+ T cells, but the cells of nonprogressors function better.


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The above story is based on materials provided by NIH/National Institute Of Allergy And Infectious Diseases. Note: Materials may be edited for content and length.


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NIH/National Institute Of Allergy And Infectious Diseases. "Study Shows Why Some Immune Systems Control HIV." ScienceDaily. ScienceDaily, 8 October 2002. <www.sciencedaily.com/releases/2002/10/021008064853.htm>.
NIH/National Institute Of Allergy And Infectious Diseases. (2002, October 8). Study Shows Why Some Immune Systems Control HIV. ScienceDaily. Retrieved April 19, 2014 from www.sciencedaily.com/releases/2002/10/021008064853.htm
NIH/National Institute Of Allergy And Infectious Diseases. "Study Shows Why Some Immune Systems Control HIV." ScienceDaily. www.sciencedaily.com/releases/2002/10/021008064853.htm (accessed April 19, 2014).

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