Featured Research

from universities, journals, and other organizations

Researchers Discover Ancient Origins Of Tuberculosis-causing Bacteria

Date:
August 20, 2005
Source:
Public Library of Science
Summary:
In the new open access journal PLoS Pathogens, researchers report that M. tuberculosis and related strains recently emerged from a much more ancient bacterial strain.

Researchers have long considered tuberculosis, a bacterial respiratorydisease that kills 3 million people each year, a relatively recenthuman affliction. But a new study in PLoS Pathogens suggests that the disease and the pathogens responsible are much older than previously thought.

Related Articles


"Our results change the current paradigm of the recent origin oftuberculosis," says Veronique Vincent, senior author of the study andresearcher at Institut Pasteur, Paris, France. These results may haveimportant future implications for improving diagnosis and treatment ofthe disease.

Most tuberculosis cases are caused by Mycobacterium tuberculosis andits close relatives. However, some tuberculosis patients from EastAfrica are infected with unusual bacterial strains that form coloniesthat appear physically different from M. tuberculosis. Using geneticdata from the different strains, Vincent and her colleagues discoveredthat the ancestors of these bacterial strains were also the progenitorsof M. tuberculosis.

These results suggest that M. tuberculosis and related strains recentlyemerged from a much more ancient bacterial species than previouslythought, possibly as old as 3 million years, Vincent says."Tuberculosis could thus be much older than the plague, typhoid fever,or malaria, and might have affected early hominids," and its expansionto the rest of the world may have coincided with the waves of humanmigration out of Africa.

###

Citation: Gutierrez MC, Brisse S, Brosch R, Fabre M, Omaýs B, et al.(2005) Ancient origin and gene mosaicism of the progenitor ofMycobacterium tuberculosis. PLoS Pathog 1(1): e5.



Story Source:

The above story is based on materials provided by Public Library of Science. Note: Materials may be edited for content and length.


Cite This Page:

Public Library of Science. "Researchers Discover Ancient Origins Of Tuberculosis-causing Bacteria." ScienceDaily. ScienceDaily, 20 August 2005. <www.sciencedaily.com/releases/2005/08/050819130824.htm>.
Public Library of Science. (2005, August 20). Researchers Discover Ancient Origins Of Tuberculosis-causing Bacteria. ScienceDaily. Retrieved December 22, 2014 from www.sciencedaily.com/releases/2005/08/050819130824.htm
Public Library of Science. "Researchers Discover Ancient Origins Of Tuberculosis-causing Bacteria." ScienceDaily. www.sciencedaily.com/releases/2005/08/050819130824.htm (accessed December 22, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, December 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Touch-Free Smart Phone Empowers Mobility-Impaired

Touch-Free Smart Phone Empowers Mobility-Impaired

Reuters - Innovations Video Online (Dec. 21, 2014) — A touch-free phone developed in Israel enables the mobility-impaired to operate smart phones with just a movement of the head. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Earthworms Provide Cancer-Fighting Bacteria

Earthworms Provide Cancer-Fighting Bacteria

Reuters - Innovations Video Online (Dec. 21, 2014) — Polish scientists isolate bacteria from earthworm intestines which they say may be used in antibiotics and cancer treatments. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Existing Chemical Compounds Could Revive Failing Antibiotics, Says Danish Scientist

Existing Chemical Compounds Could Revive Failing Antibiotics, Says Danish Scientist

Reuters - Innovations Video Online (Dec. 21, 2014) — A team of scientists led by Danish chemist Jorn Christensen says they have isolated two chemical compounds within an existing antipsychotic medication that could be used to help a range of failing antibiotics work against killer bacterial infections, such as Tuberculosis. Jim Drury went to meet him. Video provided by Reuters
Powered by NewsLook.com
Hugging It Out Could Help You Ward Off A Cold

Hugging It Out Could Help You Ward Off A Cold

Newsy (Dec. 21, 2014) — Carnegie Mellon researchers found frequent hugs can help people avoid stress-related illnesses. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins