Featured Research

from universities, journals, and other organizations

Serotonin, Acting In A Specific Brain Region, Promotes Sleep In Fruit Flies

Date:
June 6, 2006
Source:
Cell Press
Summary:
Researchers have found that the neurotransmitter serotonin, known to affect many behaviors, also appears to promote lasting, quality sleep in an animal model for understanding how sleep is regulated. While central to the lives of most animals, the proper regulation sleep remains a largely enigmatic process.

Researchers have found that the neurotransmitter serotonin, known to affect many behaviors, also appears to promote lasting, quality sleep in an animal model for understanding how sleep is regulated. While central to the lives of most animals, the proper regulation sleep remains a largely enigmatic process.

The findings are reported by Quan Yuan, William Joiner, and Amita Sehgal at the University of Pennsylvania, and appear in the June 6th issue of Current Biology.

The fruit fly, Drosophila melanogaster, is now established as a useful model for sleep research. The simple nervous system of the fly enables researchers to ask basic questions about sleep regulation and function that have been difficult to address in the more complicated mammalian systems.

Using the fly model in their new study, the researchers showed that pharmacological treatment with serotonin increases the amount, as well as the quality, of sleep. Serotonin even improves sleep in certain mutant flies that normally sleep less or have fragmented sleep, suggesting that serotonin treatment can overcome some deficits caused by other sleep problems. The researchers also identified a serotonin receptor that affects sleep, and showed that it acts in a specific region of the fly brain known as the mushroom bodies. Interestingly, the mushroom bodies are required for learning and memory in flies. Given that consolidation of memory is one of the functions hypothesized for sleep, and that serotonin is known to be involved in learning and memory in other animals, it is possible that the effect of serotonin on sleep is related to its role in learning and memory.

The researchers include Quan Yuan, William Joiner, and Amita Sehgal of the Howard Hughes Medical Institute and University of Pennsylvania School of Medicine in Philadelphia, Pennsylvania.

Yuan et al.: "A Sleep-Promoting Role for the Drosophila Serotonin Receptor 1A." Publishing in Current Biology 16, 1051βοΏ½"1062, June 6, 2006 DOI 10.1016/j.cub.2006.04.032 www.current-biology.com


Story Source:

The above story is based on materials provided by Cell Press. Note: Materials may be edited for content and length.


Cite This Page:

Cell Press. "Serotonin, Acting In A Specific Brain Region, Promotes Sleep In Fruit Flies." ScienceDaily. ScienceDaily, 6 June 2006. <www.sciencedaily.com/releases/2006/06/060605200708.htm>.
Cell Press. (2006, June 6). Serotonin, Acting In A Specific Brain Region, Promotes Sleep In Fruit Flies. ScienceDaily. Retrieved August 22, 2014 from www.sciencedaily.com/releases/2006/06/060605200708.htm
Cell Press. "Serotonin, Acting In A Specific Brain Region, Promotes Sleep In Fruit Flies." ScienceDaily. www.sciencedaily.com/releases/2006/06/060605200708.htm (accessed August 22, 2014).

Share This




More Mind & Brain News

Friday, August 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Lost Brain Cells To Blame For Sleep Problems Among Seniors

Lost Brain Cells To Blame For Sleep Problems Among Seniors

Newsy (Aug. 21, 2014) — According to a new study, elderly people might have trouble sleeping because of the loss of a certain group of neurons in the brain. Video provided by Newsy
Powered by NewsLook.com
Do More Wedding Guests Make A Happier Marriage?

Do More Wedding Guests Make A Happier Marriage?

Newsy (Aug. 20, 2014) — A new study found couples who had at least 150 guests at their weddings were more likely to report being happy in their marriages. Video provided by Newsy
Powered by NewsLook.com
Charter Schools Alter Post-Katrina Landscape

Charter Schools Alter Post-Katrina Landscape

AP (Aug. 20, 2014) — Nine years after Hurricane Katrina, charter schools are the new reality of public education in New Orleans. The state of Louisiana took over most of the city's public schools after the killer storm in 2005. (Aug. 20) Video provided by AP
Powered by NewsLook.com
Researcher Testing on-Field Concussion Scanners

Researcher Testing on-Field Concussion Scanners

AP (Aug. 19, 2014) — Four Texas high school football programs are trying out an experimental system designed to diagnose concussions on the field. The technology is in response to growing concern over head trauma in America's most watched sport. (Aug. 19) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins