Featured Research

from universities, journals, and other organizations

Secrets of internal cell fine-tuning uncovered

Date:
July 29, 2014
Source:
University of Kent
Summary:
Scientists have shown for the first time how the structures inside cells are regulated -- a breakthrough that could have a major impact on cancer therapy development. The team uncovered the mechanism whereby the physical properties of the internal structures within cells -- known as actin filaments -- are 'fine-tuned' to undertake different functions.

New research from scientists at the University of Kent has shown for the first time how the structures inside cells are regulated -- a breakthrough that could have a major impact on cancer therapy development.

Related Articles


A team from Kent's School of Biosciences uncovered the mechanism whereby the physical properties of the internal structures within cells -- known as actin filaments -- are 'fine-tuned' to undertake different functions.

While some of these actin filaments appear to completely stable, providing a framework for the cell, others are more dynamic, allowing the cell to respond rapidly to changes in its environment.

The researchers -- PhD students Matthew Johnson and Daniel East, who were led by Dr Daniel Mulvihill -- used yeast cells to mimic those in humans. They utilized a novel biology 'trick' to switch the location of molecules which bind to, and stabilise, the actin polymer and modulate the movement of molecular motors.

In this way, they uncovered the mechanism which determines the functional characteristics of actin filaments in all cells and orchestrates cellular activity. It is expected the breakthrough could have a major impact on the development of therapies for a variety of diseases, including cancer.


Story Source:

The above story is based on materials provided by University of Kent. Note: Materials may be edited for content and length.


Journal Reference:

  1. Matthew Johnson, DanielA. East, DanielP. Mulvihill. Formins Determine the Functional Properties of Actin Filaments in Yeast. Current Biology, 2014; 24 (13): 1525 DOI: 10.1016/j.cub.2014.05.034

Cite This Page:

University of Kent. "Secrets of internal cell fine-tuning uncovered." ScienceDaily. ScienceDaily, 29 July 2014. <www.sciencedaily.com/releases/2014/07/140729093114.htm>.
University of Kent. (2014, July 29). Secrets of internal cell fine-tuning uncovered. ScienceDaily. Retrieved December 22, 2014 from www.sciencedaily.com/releases/2014/07/140729093114.htm
University of Kent. "Secrets of internal cell fine-tuning uncovered." ScienceDaily. www.sciencedaily.com/releases/2014/07/140729093114.htm (accessed December 22, 2014).

Share This


More From ScienceDaily



More Plants & Animals News

Monday, December 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Earthworms Provide Cancer-Fighting Bacteria

Earthworms Provide Cancer-Fighting Bacteria

Reuters - Innovations Video Online (Dec. 21, 2014) Polish scientists isolate bacteria from earthworm intestines which they say may be used in antibiotics and cancer treatments. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Existing Chemical Compounds Could Revive Failing Antibiotics, Says Danish Scientist

Existing Chemical Compounds Could Revive Failing Antibiotics, Says Danish Scientist

Reuters - Innovations Video Online (Dec. 21, 2014) A team of scientists led by Danish chemist Jorn Christensen says they have isolated two chemical compounds within an existing antipsychotic medication that could be used to help a range of failing antibiotics work against killer bacterial infections, such as Tuberculosis. Jim Drury went to meet him. Video provided by Reuters
Powered by NewsLook.com
Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
Monarch Butterflies Descend Upon Mexican Forest During Annual Migration

Monarch Butterflies Descend Upon Mexican Forest During Annual Migration

Reuters - Light News Video Online (Dec. 19, 2014) Millions of monarch butterflies begin to descend onto Mexico as part of their annual migration south. Rough Cut (no reporter narration) Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins