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Too much salt could potentially contribute to liver damage

Date:
February 24, 2016
Source:
American Chemical Society
Summary:
A sprinkle of salt can bring out the flavor of just about any dish. However, it's well known that too much can lead to high blood pressure, a potentially dangerous condition if left untreated. Now scientists report a new animal study that found a high-salt diet might also contribute to liver damage in adults and developing embryos.
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A sprinkle of salt can bring out the flavor of just about any dish. However, it's well known that too much can lead to high blood pressure, a potentially dangerous condition if left untreated. Now scientists report a new animal study that found a high-salt diet might also contribute to liver damage in adults and developing embryos. It appears in ACS' Journal of Agricultural and Food Chemistry.

Our bodies need a small amount of salt -- the U.S. government recommends one teaspoon per day if you are a healthy adult. Among other functions, the sodium ions from the savory mineral help regulate water movement within the body and conduct nerve impulses. But most Americans eat too much salt. Some research indicates that in addition to high blood pressure, overconsumption of sodium can damage the liver. Xuesong Yang and colleagues wanted to explore the potential effect at a cellular level.

The researchers gave adult mice a high-salt diet and exposed chick embryos to a briny environment. Excessive sodium was associated with a number of changes in the animals' livers, including oddly shaped cells, an increase in cell death and a decrease in cell proliferation, which can contribute to the development of fibrosis. On a positive note, the researchers did find that treating damaged cells with vitamin C appeared to partially counter the ill effects of excess salt.


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The above post is reprinted from materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Guang Wang, Cheung-kwan Yeung, Wing-Yan Wong, Nuan Zhang, Yi-fan Wei, Jing-li Zhang, Yu Yan, Ching-yee Wong, Jun-jie Tang, Manli Chuai, Kenneth Ka Ho Lee, Li-jing Wang, Xuesong Yang. Liver Fibrosis Can Be Induced by High Salt Intake through Excess Reactive Oxygen Species (ROS) Production. Journal of Agricultural and Food Chemistry, 2016; 64 (7): 1610 DOI: 10.1021/acs.jafc.5b05897

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American Chemical Society. "Too much salt could potentially contribute to liver damage." ScienceDaily. ScienceDaily, 24 February 2016. <www.sciencedaily.com/releases/2016/02/160224151015.htm>.
American Chemical Society. (2016, February 24). Too much salt could potentially contribute to liver damage. ScienceDaily. Retrieved July 25, 2016 from www.sciencedaily.com/releases/2016/02/160224151015.htm
American Chemical Society. "Too much salt could potentially contribute to liver damage." ScienceDaily. www.sciencedaily.com/releases/2016/02/160224151015.htm (accessed July 25, 2016).

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