Cystic Fibrosis News
August 29, 2016

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More Cystic Fibrosis News
August 29, 2016

Benefits of Cystic Fibrosis Drug Ivacaftor Reported in Pre-School Children for the First Time

Jan. 20, 2016 — The oral drug ivacaftor appears to be safe and could be beneficial to young children between the ages of 2 and 5 with a specific type of cystic fibrosis, according to new research. The findings also ... read more

Researchers Further Illuminate Pathway for Treatment of Cystic Fibrosis

Jan. 12, 2016 — New research findings add further clarity to a question that has polarized the cystic fibrosis (CF) research community. It is well established that people with cystic fibrosis have two faulty copies ... read more

Ethnic Differences in Cystic Fibrosis Genetic Coding Not Addressed in Screening Tests for Nonwhite Patients

Dec. 16, 2015 — Cystic fibrosis (CF) occurs less frequently in nonwhites than in whites, and nonwhites tend to be diagnosed at a later age. Delaying diagnosis can result in postponed treatment and clinical ... read more

Protein 'Talks' to Wrong Partners in Cystic Fibrosis, Scientists Find

Nov. 30, 2015 — Evidence has been found that a mutant protein responsible for most cases of cystic fibrosis is so busy "talking" to the wrong cellular neighbors that it cannot function normally and is ... read more

Nov. 20, 2015 — Fungi in the mucus of patients with cystic fibrosis has been examined by researchers who have discovered how one particularly cunning fungal species has evolved to defend itself against neighboring ... read more

Gene Therapy: Promising Candidate for Cystic Fibrosis Treatment

Nov. 16, 2015 — An improved gene therapy treatment can cure mice with cystic fibrosis (CF). Cell cultures from CF patients, too, respond well to the treatment, suggest new encouraging ... read more

Microscopic View of Coughed-Up Mucus May Be New Biomarker for Cystic Fibrosis Progression

Oct. 14, 2015 — Researchers have been studying mucus in the lungs of cystic fibrosis patients, and their primary goal was to design inhalable therapeutic nanoparticles that cross the cystic fibrosis mucus barrier in ... read more

Five Genetic Regions Implicated in Cystic Fibrosis Severity

Sep. 29, 2015 — If you have two faulty copies of the CFTR gene, you will have cystic fibrosis. But the severity of your disease will depend partly on many other genes. Now, researchers report that five regions of ... read more

Gel Study Uncovers Unexpected Dynamics

Sep. 24, 2015 — Important new information about the dynamics of bacterial gels has been revealed by research, which could ultimately suggest new ways of helping prevent or better control diseases such as cystic ... read more

Tackling the Root Cause of Cystic Fibrosis

Aug. 26, 2015 — Treatments for cystic fibrosis (CF) have added years to the lives of thousands of Americans. But they can be difficult to administer, and most don't fix the underlying cause. Scientists have now ... read more

Aug. 20, 2015 — Treatments for the same opportunistic bacteria found in cystic fibrosis patients can work in one area in the lung and be less effective in others. The reason, researchers report, is that bacteria ... read more

Nanoparticles Used to Breach Mucus Barrier in Lungs

Aug. 3, 2015 — A DNA-loaded nanoparticle has been designed that can pass through the mucus barrier covering conducting airways of lung tissue. Nanotechnology could one day provide an inhaled vehicle to deliver ... read more

Cystic Fibrosis Microorganisms Survive on Little to No Oxygen

July 28, 2015 — Microbes contributing to cystic fibrosis are able to survive in saliva and mucus that is chemically heterogeneous, including significant portions that are largely devoid of oxygen, according to a ... read more

Cystic Fibrosis Deadlier for Hispanic Than Non-Hispanic Patients, Study Finds

June 24, 2015 — Cystic fibrosis is more deadly for Hispanic than non-Hispanic patients, a disparity that is not explained by differences in their access to health care, according to a new ... read more

Lung Transplant Survival Rates Good for Cystic Fibrosis Patients

June 15, 2015 — The five-year survival rate for Canadians with cystic fibrosis who have received a lung transplant is 67 percent, new research finds. Cystic fibrosis is an inherited chronic disease that affects the ... read more

Novel Drug Combo Improves Function of Cystic Fibrosis Protein

May 20, 2015 — A novel two-drug combination has the potential to target and restore a defective protein underlying cystic fibrosis (CF), according to two phase III clinical trials conducted at 187 medical centers ... read more

Key Component in Protein That Causes Cystic Fibrosis Identified

May 19, 2015 — Nearly 70,000 people worldwide are living with cystic fibrosis, a life-threatening genetic disease. There currently is no cure for the condition, but researchers have now identified a key component ... read more

Female Cystic Fibrosis Patients Need More Contraceptive Guidance, Study Finds

May 7, 2015 — Only half of women with cystic fibrosis report using contraception and frequently apt to become pregnant unintentionally, according to a new study. As recently as the 1960s, children with cystic ... read more

Potential New Treatments for Toxoplasma-Induced Pneumonia and Cystic Fibrosis

Apr. 29, 2015 — New research has discovered a link between a vital pumping system that does not function correctly in people with cystic fibrosis and the parasite Toxoplasma. This is the first time a causal ... read more

Gene Editing Used to Correct Mutation in Cystic Fibrosis

Apr. 27, 2015 — Researchers have successfully corrected the most common mutation in the gene that causes cystic fibrosis. Cystic fibrosis is an inherited, life-threatening disorder that damages the lungs and ... read more

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